Medial Temporal Cortices in Ex Vivo Magnetic Resonance Imaging

被引:14
|
作者
Augustinack, Jean C. [1 ]
van der Kouwe, Andre J. W. [1 ]
Fischl, Bruce [1 ,2 ]
机构
[1] MGH, Dept Radiol, Athinoula A Martinos Ctr, Charlestown, MA 02129 USA
[2] MIT, Comp Sci & AI Lab, Cambridge, MA 02139 USA
关键词
cortical localization; entorhinal cortex; verrucae; perirhinal cortex; perforant pathway; HIGH-RESOLUTION MRI; MILD COGNITIVE IMPAIRMENT; HUMAN PERIRHINAL CORTEX; HUMAN CEREBRAL-CORTEX; ENTORHINAL CORTEX; ALZHEIMERS-DISEASE; PARAHIPPOCAMPAL GYRUS; HUMAN-BRAIN; LAYER-II; AREA; 35;
D O I
10.1002/cne.23432
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This review focuses on the ex vivo magnetic resonance imaging (MRI) modeling of medial temporal cortices and associated structures, the entorhinal verrucae and the perforant pathway. Typical in vivo MRI has limited resolution due to constraints on scan times and does not show laminae in the medial temporal lobe. Recent studies using ex vivo MRI have demonstrated lamina in the entorhinal, perirhinal, and hippocampal cortices. These studies have enabled probabilistic brain mapping that is based on the ex vivo MRI contrast, validated to histology, and subsequently mapped onto an in vivo spherically warped surface model. Probabilistic maps are applicable to other in vivo studies. J. Comp. Neurol. 521:4177-4188, 2013. (c) 2013 Wiley Periodicals, Inc.
引用
收藏
页码:4177 / 4188
页数:12
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