Genetic analysis in fine-needle aspiration of the thyroid: A new tool for the clinic

被引:21
|
作者
Russo, D [1 ]
Arturi, F
Pontecorvi, A
Filetti, S
机构
[1] Univ Catanzaro, Cattedra Farmacol, Fac Farm, Catanzaro, Italy
[2] Univ Catanzaro, Cattedra Endocrinol, Dipartimento Med Sperimentale & Clin, Catanzaro, Italy
[3] Univ Cattolica Sacro Cuore, Ist Tumori Regina Elena, Lab Oncogenesi Mol, Rome, Italy
[4] Univ Cattolica Sacro Cuore, Cattedra Endocrinol, Ist Patol Med, Rome, Italy
来源
关键词
D O I
10.1016/S1043-2760(99)00169-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This review will examine the application of genetic analysis to cytological specimens obtained by fine-needle aspiration biopsy in the management of thyroid tumours. In particular it will consider the use of polymerase chain reaction-based techniques in the diagnosis of the micrometastasis of differentiated thyroid carcinoma to cervical lymph nodes, as well as in the defection of oncogenic alterations in solid thyroid nodules.
引用
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页码:280 / 285
页数:6
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