Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?

被引：9

作者：

Correa, Thiago Domingos ^{[1
,2
,3
]}

Jakob, Stephan Matthias ^{[2
,3
]}

Takala, Jukka ^{[2
,3
]}

机构：

[1] Hosp Israelita Albert Einstein, Intens Care Unit, BR-05652000 Sao Paulo, Brazil

[2] Univ Hosp Bern, Inselspital, Dept Intens Care Med, CH-3010 Bern, Switzerland

[3] Univ Bern, CH-3010 Bern, Switzerland

来源：

CRITICAL CARE | 2015年 / 19卷

关键词：

VASOPRESSOR LOAD; INTENSIVE-CARE; RENAL-FUNCTION; NOREPINEPHRINE; MULTICENTER; MORTALITY; PERFUSION; SEPSIS; FLOW;

D O I：

10.1186/s13054-015-0958-x

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasing arterial blood pressure improved sublingual microcirculation parameters, no concomitant improvement in systemic tissue perfusion indicators was found. Here, we discuss why resuscitation targets may need to be individualized, taking into account the patient's baseline condition, and present directions for future research in this field.

引用

页数：2

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