Clinical target volume delineation for radiotherapy of the esophagus

被引:9
|
作者
Lazarescu, I. [1 ]
Thureau, S. [1 ]
Nkhali, L. [1 ]
Pradier, O. [2 ]
Dubray, B. [1 ]
机构
[1] Ctr Henri Becquerel, QuantIF Litis EA4108, Dept Radiotherapie & Phys Med, F-76000 Rouen, France
[2] CHU Morvan, Dept Oncol Radiotherapie, F-29200 Brest, France
来源
CANCER RADIOTHERAPIE | 2013年 / 17卷 / 5-6期
关键词
Esophageal cancer; Conformal radiotherapy; FDG-PET; Clinical target volume; Positive predictive value; Negative predictive value; SQUAMOUS-CELL CARCINOMA; POSITRON-EMISSION-TOMOGRAPHY; LYMPH-NODE; CONCURRENT CHEMOTHERAPY; PROGNOSTIC-FACTORS; RADIATION-THERAPY; CANCER; PATTERN; JUNCTION; IMPACT;
D O I
10.1016/j.canrad.2013.07.145
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The dense lymphatic network of the esophagus facilitates tumour spreading along the cephalo-caudal axis and to locoregional lymph nodes. A better understanding of microscopic invasion by tumour cells, based on histological analysis of surgical specimens and analysis of recurrence sites, has justified a reduction in radiotherapy target volumes. The delineation of the clinical target volume (CTV) depends on tumour characteristics (site, histology) and on its spread as assessed on endoscopic ultrasonography and (F-18)-flurodeoxyglucose positron-emission tomography (FDG-PET). We propose that positive and negative predictive values for FOG-PET should be used to adapt the CTV according to the risk of nodal involvement. (C) 2013 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:453 / 460
页数:8
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