Cloning and characterization of a protein phosphatase type 1-binding subunit from smooth muscle similar to the glycogen-binding subunit of liver

被引:8
|
作者
Hirano, K [1 ]
Hirano, M [1 ]
Hartshorne, DJ [1 ]
机构
[1] UNIV ARIZONA, MUSCLE BIOL GRP, TUCSON, AZ 85721 USA
关键词
smooth muscle; glycogen-binding subunit; protein phosphatase type 1; yeast two-hybrid system;
D O I
10.1016/S0167-4838(97)00048-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A yeast two-hybrid screen of a chicken gizzard cDNA library detected the interaction of the catalytic subunit of protein phosphatase type 1 with a novel subunit. Subsequent characterization established similarity (58%) to the rat liver glycogen-binding subunit. Northern analyses showed expression in a wide range of tissues.
引用
收藏
页码:177 / 180
页数:4
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