Oviz-Bio: a web-based platform for interactive cancer genomics data visualization

被引:18
|
作者
Jia, Wenlong [1 ]
Li, Hechen [1 ]
Li, Shiying [1 ]
Chen, Lingxi [1 ]
Li, Shuai Cheng [1 ,2 ]
机构
[1] City Univ Hong Kong, Dept Comp Sci, Kowloon Tong, Hong Kong 999077, Peoples R China
[2] City Univ Hong Kong, Dept Biomed Engn, Kowloon Tong, Hong Kong 999077, Peoples R China
关键词
MOLECULAR CHARACTERIZATION; WHOLE-GENOME; CELL; INTEGRATION; LANDSCAPE; GENES; EXOME;
D O I
10.1093/nar/gkaa371
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Genetics data visualization plays an important role in the sharing of knowledge from cancer genome research. Many types of visualization are widely used, most of which are static and require sufficient coding experience to create. Here, we present Oviz-Bio, a web-based platform that provides interactive and real-time visualizations of cancer genomics data. Researchers can interactively explore visual outputs and export high-quality diagrams. Oviz-Bio supports a diverse range of visualizations on common cancer mutation types, including annotation and signatures of small scale mutations, haplotype view and focal clusters of copy number variations, split-reads alignment and heatmap view of structural variations, transcript junction of fusion genes and genomic hotspot of oncovirus integrations. Furthermore, Oviz-Bio allows landscape view to investigate multi-layered data in samples cohort. All Oviz-Bio visual applications are freely available at https://bio.oviz.org/.
引用
收藏
页码:W415 / W426
页数:12
相关论文
共 50 条
  • [1] Oviz-Bio: a web-based platform for interactive cancer genomics data visualization (vol 48, pg W415, 2020)
    Jia, Wenlong
    Li, Hechen
    Li, Shiying
    Chen, Lingxi
    Li, Shuai Cheng
    [J]. NUCLEIC ACIDS RESEARCH, 2020, 48 (14) : 8203 - 8204
  • [2] Web-based interactive visualization of data cubes
    Wang, XS
    Chen, P
    Ding, W
    [J]. MSV '05: PROCEEDINGS OF THE 2005 INTERNATIONAL CONFERENCE ON MODELING, SIMULATION AND VISUALIZATION METHODS, 2005, : 136 - 143
  • [3] Web-Based Data Visualization Platform for MATSim
    Charlton, Billy
    Laudan, Janek
    [J]. TRANSPORTATION RESEARCH RECORD, 2020, 2674 (10) : 124 - 133
  • [4] Mian: interactive web-based microbiome data table visualization and machine learning platform
    Jin, Boyang Tom
    Xu, Feng
    Ng, Raymond T.
    Hogg, James C.
    [J]. BIOINFORMATICS, 2022, 38 (04) : 1176 - 1178
  • [5] CPA: a web-based platform for consensus pathway analysis and interactive visualization
    Nguyen, Hung
    Tran, Duc
    Galazka, Jonathan M.
    Costes, Sylvain, V
    Beheshti, Afshin
    Petereit, Juli
    Draghici, Sorin
    Nguyen, Tin
    [J]. NUCLEIC ACIDS RESEARCH, 2021, 49 (W1) : W114 - W124
  • [6] Interactive Web-Based Visualization of Multidimensional Physical and Astronomical Data
    Diblen, Faruk
    Hendriks, Luc
    Stienen, Bob
    Caron, Sascha
    Bakhshi, Rena
    Attema, Jisk
    [J]. FRONTIERS IN BIG DATA, 2021, 4
  • [7] Wiz: A Web-Based Tool for Interactive Visualization of Big Data
    Balzer, Christopher
    Oktavian, Rama
    Zandi, Mohammad
    Fairen-Jimenez, David
    Moghadam, Peyman Z.
    [J]. PATTERNS, 2020, 1 (08):
  • [8] Interactive web-based data visualization with R, plotly, and shiny
    Li, Ran
    Bilal, Usama
    [J]. BIOMETRICS, 2021, 77 (02) : 776 - 777
  • [9] Interactive web-based data visualization with R, plotly, and shiny
    Shalabh
    [J]. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 2021, 184 (03) : 1150 - 1150
  • [10] A web-based, interactive visualization tool for social environmental survey data
    Jones, Amber Spackman
    Horsburgh, Jeffery S.
    Jackson-Smith, Douglas
    Ramirez, Maurier
    Flint, Courtney G.
    Caraballo, Juan
    [J]. ENVIRONMENTAL MODELLING & SOFTWARE, 2016, 84 : 412 - 426