MKP-1 mediates anti-inflammatory effects of the PDE4 inhibitor rolipram

被引：0
|
作者：
Korhonen, R.
Hommo, T.
Laavola, M.
Keranen, T.
Hamalainen, M.
Moilanen, E.
机构：
[1] Univ Tampere, Sch Med, Immunopharmacol Res Grp, FIN-33101 Tampere, Finland
[2] Tampere Univ Hosp, Tampere, Finland
来源：
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY | 2013年 / 42卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：427 / 428
页数：2
相关论文
共 50 条
  • [31] Chf6001 Is A Novel Highly Potent And Selective Phosphodiesterase 4 (pde4) Inhibitor With A Robust In Vitro Anti-Inflammatory Profile
    Moretto, N.
    Caruso, P.
    Marchini, G.
    Bosco, R.
    Carnini, C.
    Civelli, M.
    Villetti, G.
    Facchinetti, F.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 189
  • [32] In vitro pharmacological characterization of CHF6001, a novel selective phosphodiesterase 4 (PDE4) inhibitor with a robust anti-inflammatory profile
    Facchinetti, Fabrizio
    Moretto, Nadia
    Caruso, Paola
    Marchini, Gessica
    Bosco, Raffaella
    Carnini, Chiesa
    Civelli, Maurizio
    Villetti, Gino
    EUROPEAN RESPIRATORY JOURNAL, 2014, 44
  • [33] The histone deacetylase inhibitor, trichostatin A (TSA), exhibits anti-inflammatory properties via induction of MKP-1 mediated suppression of pro-inflammatory cytokines.
    Maslach-Hubbard, Anna
    Cai, Qing
    Shauley, Thomas P.
    CRITICAL CARE MEDICINE, 2007, 35 (12) : A31 - A31
  • [34] Impaired host defense to Klebsiella pneumoniae infection in mice treated with the PDE4 inhibitor rolipram
    Soares, AC
    Souza, DG
    Pinho, V
    Vieira, AT
    Barsante, MM
    Nicoli, JR
    Teixeira, M
    BRITISH JOURNAL OF PHARMACOLOGY, 2003, 140 (05) : 855 - 862
  • [35] Can the anti-inflammatory potential of PDE4 inhibitors be realized: guarded optimism or wishful thinking?
    Giembycz, M. A.
    BRITISH JOURNAL OF PHARMACOLOGY, 2008, 155 (03) : 288 - 290
  • [36] Anti-Inflammatory Potential Of Novel Pde4 Inhibitors Derived From Chinese Medicine Forsythia
    Coon, T.
    Weathington, N.
    Chen, B.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 189
  • [37] The anti-depressant effects of a novel PDE4 inhibitor derived from resveratrol
    Yu, Yingcong
    Wang, Jinhui
    Huang, Xianfeng
    PHARMACEUTICAL BIOLOGY, 2021, 59 (01) : 418 - 423
  • [38] Pyridazinone derivatives as potential anti-inflammatory agents: synthesis and biological evaluation as PDE4 inhibitors
    Allart-Simon, Ingrid
    Moniot, Aurelie
    Bisi, Nicolo
    Ponce-Vargas, Miguel
    Audonnet, Sandra
    Laronze-Cochard, Marie
    Sapi, Janos
    Henon, Eric
    Velard, Frederic
    Gerard, Stephane
    RSC MEDICINAL CHEMISTRY, 2021, 12 (04): : 584 - 592
  • [39] Combined anti-inflammatory effects of β2-adrenergic agonists and PDE4 inhibitors on astrocytes by upregulation of intracellular cAMP
    Christiansen, S. H.
    Selige, J.
    Dunkern, T.
    Rassov, A.
    Leist, M.
    NEUROCHEMISTRY INTERNATIONAL, 2011, 59 (06) : 837 - 846
  • [40] THE PDE4 INHIBITOR ROLIPRAM SUPPRESSES TGF-BETA1-STIMULATED MCP-1 EXPRESSION IN MESANGIAL CELLS
    Grande, Joseph
    Cheng, Jingfei
    Gray, Catherine E.
    Warner, Gina M.
    Encarnacion, Montserrat Diaz
    NEPHROLOGY, 2005, 10 : A117 - A117
12345