An atom efficient, green synthesis of 2-pyrazoline derivatives under solvent-free conditions using grinding technique

被引:27
|
作者
Zangade, Sainath B. [1 ]
Mokle, Shyam S. [1 ]
Shinde, Avinash T. [1 ]
Vibhute, Yeshwant B. [1 ]
机构
[1] Yeshwant Mahavidyalaya, Organ Synth Lab, Dept Studies Chem, Nanded 431602, MS, India
关键词
2-hydroxychalcones; 2-pyrazolines; solvent free; grinding technique; green chemistry; PYRAZOLINES; ANTIDEPRESSANT; ABSENCE;
D O I
10.1080/17518253.2012.713123
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple, rapid, efficient, and environmentally benign procedure for synthesis of 2-pyrazoline derivatives has been achieved by reacting 2-hydroxychalcones with hydrazine hydrate under solvent-free grinding technique. The short reaction time, cleaner reaction, easy workup, higher yields, and mild reaction conditions make this protocol practical and economically attractive in comparison with the classical reaction. [GRAPHICS] .
引用
收藏
页码:123 / 127
页数:5
相关论文
共 50 条
  • [41] Efficient and Novel Synthesis of Benzoxazole Derivatives in the Presence of Zinc Dust Under Solvent-Free Conditions
    Murty, M. S. R.
    Ram, Kesur R.
    Rao, Rayudu Venkateswara
    Yadav, J. S.
    SYNTHETIC COMMUNICATIONS, 2010, 40 (19) : 2844 - 2849
  • [42] An efficient method for synthesis of 4-(phosphonomethyl)benzene derivatives under solvent-free conditions
    Yang, T
    Lin, CX
    Fu, H
    Jiang, YY
    Zhao, YF
    SYNTHETIC COMMUNICATIONS, 2004, 34 (06) : 1017 - 1022
  • [43] L-Proline as an efficient organocatalyst for the synthesis of quinoxaline derivatives under solvent-free conditions
    Ezabadi, A. (aliezabadi@yahoo.com), 1848, Sharif University of Technology (20):
  • [44] SILICA-GEL-CATALYZED EFFICIENT SYNTHESIS OF QUINOXALINE DERIVATIVES UNDER SOLVENT-FREE CONDITIONS
    Nandi, Ganesh Chandra
    Samai, Subhasis
    Kumar, Ram
    Singh, M. S.
    SYNTHETIC COMMUNICATIONS, 2011, 41 (03) : 417 - 425
  • [45] L-proline as an efficient organocatalyst for the synthesis of quinoxaline derivatives under solvent-free conditions
    Ezabadi, A.
    Farrokhinia, N.
    SCIENTIA IRANICA, 2013, 20 (06) : 1848 - 1854
  • [46] Nano Clinoptilolite: Highly Efficient Catalyst for the Synthesis of Chromene Derivatives Under Solvent-Free Conditions
    Hallajian, Sara
    Khalilzadeh, Mohammad A.
    Tajbakhsh, Mahgol
    Alipour, Eskandar
    Safaei, Zahra
    COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2015, 18 (05) : 486 - 491
  • [47] Green synthesis of aurones and related compounds under solvent-free conditions
    Boussafi, Karima
    Villemin, Didier
    Bar, Nathalie
    Belghosi, Mabrouk
    JOURNAL OF CHEMICAL RESEARCH, 2016, (09) : 567 - 569
  • [48] Ultrasound assisted green synthesis of α-hydroxyphosphonates under solvent-free conditions
    Bouzina, Abdeslem
    Aouf, Nour-eddine
    Berredjem, Malika
    RESEARCH ON CHEMICAL INTERMEDIATES, 2016, 42 (06) : 5993 - 6002
  • [49] Ultrasound assisted green synthesis of α-hydroxyphosphonates under solvent-free conditions
    Abdeslem Bouzina
    Nour-eddine Aouf
    Malika Berredjem
    Research on Chemical Intermediates, 2016, 42 : 5993 - 6002
  • [50] A novel and efficient strategy for the synthesis of various carbamates using carbamoyl chlorides under solvent-free and grinding conditions using microwave irradiation
    Hassan Zare
    Mohammad Mehdi Ghanbari
    Marzieh Jamali
    Abdollah Aboodi
    Chinese Chemical Letters, 2012, 23 (08) : 883 - 886