DEVELOPMENT OF MECHANISM-BASED NOVEL DILI BIOMARKERS AND THERAPEUTIC INTERVENTIONS

被引：0
|
作者：
Antoine, Daniel J. [1 ]
机构：
[1] Univ Liverpool, Dept Mol & Clin Pharmacol, MRC Ctr Drug Safety Sci, Liverpool, Merseyside, England
来源：
DRUG METABOLISM AND PHARMACOKINETICS | 2018年 / 33卷 / 01期
关键词：
D O I：
10.1016/j.dmpk.2017.11.036
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
S13
引用
收藏
页码：S7 / S8
页数：7
相关论文
共 50 条
  • [21] Mechanism-based pharmacokinetic-pharmacodynamic modeling - A new classification of biomarkers
    Danhof, M
    Alvan, G
    Dahl, SG
    Kuhlmann, J
    Paintaud, G
    PHARMACEUTICAL RESEARCH, 2005, 22 (09) : 1432 - 1437
  • [22] Current status and future perspectives of mechanism-based liver safety biomarkers
    Antoine, Daniel
    TOXICOLOGY LETTERS, 2012, 211 : S9 - S10
  • [23] Thalamus-related anomalies as candidate mechanism-based biomarkers for psychosis
    Steullet, Pascal
    SCHIZOPHRENIA RESEARCH, 2020, 226 : 147 - 157
  • [24] Novel, selective mechanism-based inhibitors of the herpes proteases
    Pinto, IL
    West, A
    Debouck, CM
    DiLella, AG
    Gorniak, JG
    ODonnell, KC
    OShannessy, DJ
    Patel, A
    Jarvest, RL
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1996, 6 (20) : 2467 - 2472
  • [25] Novel approaches to mechanism-based atrial fibrillation ablation
    Quintanilla, Jorge G.
    Shpun, Shlomo
    Jalife, Jose
    Filgueiras-Rama, David
    CARDIOVASCULAR RESEARCH, 2021, 117 (07) : 1662 - 1681
  • [26] Antimetastatic activity of a novel mechanism-based gelatinase inhibitor
    Krüger, A
    Arlt, MJE
    Gerg, M
    Kopitz, C
    Bernardo, MM
    Chang, M
    Mobashery, S
    Fridman, R
    CANCER RESEARCH, 2005, 65 (09) : 3523 - 3526
  • [27] Development of a Mechanism-Based Next-Generation Therapeutic for Heart Failure Derived From the Dark Genome
    Viereck, Janika
    Thum, Thomas
    JACC-BASIC TO TRANSLATIONAL SCIENCE, 2023, 8 (12): : 1595 - 1598
  • [28] Mechanism-Based PKPD Projections in Exploratory Drug Development
    Kawai, Ryosei Leo
    DRUG METABOLISM AND PHARMACOKINETICS, 2009, 24 (01) : 1 - 2
  • [29] Druggable Biomarkers Altered in Clear Cell Renal Cell Carcinoma: Strategy for the Development of Mechanism-Based Combination Therapy
    Rustum, Youcef M.
    Reis, Ryan
    Rustum, Tara M.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (02)
  • [30] Stimulating the development of mechanism-based, individualized pain therapies
    Woodcock, Janet
    Witter, James
    Dionne, Raymond A.
    NATURE REVIEWS DRUG DISCOVERY, 2007, 6 (09) : 703 - 710
12345