Histone Methyltransferase Ezh2 Controls T-Cell Immunity by Regulating Bioenergetic Metabolism

被引：0
|
作者：
He, Shan [1 ]
Xie, Fang [1 ]
Tong, Qing [1 ]
Mochizuki, Kazuhiro [1 ]
Liu, Yongnian [1 ]
Lapinski, Philip E. [2 ]
Mineishi, Shin [1 ]
Mani, Ram Shankar [3 ]
Marquez, Victor E. [4 ]
Chinnaiyan, Arul M. [3 ]
King, Philip D. [2 ]
Zhang, Yi [1 ]
机构：
[1] Univ Michigan, Sch Med, Dept Internal Med, Ann Arbor, MI USA
[2] Univ Michigan, Dept Microbiol & Immunol, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Pathol, Ann Arbor, MI 48109 USA
[4] NCI, Biol Chem Lab, Ctr Canc Res, NIH, Frederick, MD 21701 USA
来源：
BLOOD | 2012年 / 120卷 / 21期
关键词：
D O I：
10.1182/blood.V120.21.953.953
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
953
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Histone methyltransferase Ezh2 is critical for activation-induced CD8 T cell proliferation and survival
    Chen, Guobing
    Subedi, Kalpana
    Mi, Jenny
    Shi, Alvin
    Weng, Nan-Ping
    JOURNAL OF IMMUNOLOGY, 2015, 194
  • [42] The Histone Methyltransferase EZH2 is Required for Cell Growth in Diffuse Large B-cell Lymphoma
    Trojer, P.
    Garapaty, S.
    Lan, F.
    Balsubramanian, V.
    Chan, E.
    Hatton, C.
    Campbell, R.
    Cummings, R.
    Normant, E.
    Bryant, B.
    EUROPEAN JOURNAL OF CANCER, 2012, 48 : 166 - 167
  • [43] Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
    Ernst, Thomas
    Chase, Andrew J.
    Score, Joannah
    Hidalgo-Curtis, Claire E.
    Bryant, Catherine
    Jones, Amy V.
    Waghorn, Katherine
    Zoi, Katerina
    Ross, Fiona M.
    Reiter, Andreas
    Hochhaus, Andreas
    Drexler, Hans G.
    Duncombe, Andrew
    Cervantes, Francisco
    Oscier, David
    Boultwood, Jacqueline
    Grand, Francis H.
    Cross, Nicholas C. P.
    NATURE GENETICS, 2010, 42 (08) : 722 - U109
  • [44] Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
    Nikoloski, Gorica
    Langemeijer, Saskia M. C.
    Kuiper, Roland P.
    Knops, Ruth
    Massop, Marion
    Tonnissen, Evelyn R. L. T. M.
    van der Heijden, Adrian
    Scheele, Theresia N.
    Vandenberghe, Peter
    de Witte, Theo
    van der Reijden, Bert A.
    Jansen, Joop H.
    NATURE GENETICS, 2010, 42 (08) : 665 - 667
  • [45] DISTINCT AND SEPARABLE ROLES FOR HISTONE METHYLTRANSFERASE EZH2 IN NEUROGENIC ASTROCYTES
    Lim, Daniel A.
    Hwang, William W.
    Salinas, Ryan D.
    Siu, Jason J.
    Kelley, Kevin W.
    Delgado, Ryan N.
    Paredes, Mercedes F.
    Alvarez-Buylla, Arturo
    Oldham, Michael C.
    Lim, Daniel A.
    NEURO-ONCOLOGY, 2014, 16
  • [46] Symphony of epigenetic and metabolic regulation-interaction between the histone methyltransferase EZH2 and metabolism of tumor
    Zhang, Tengrui
    Gong, Yueqing
    Meng, Hui
    Li, Chen
    Xue, Lixiang
    CLINICAL EPIGENETICS, 2020, 12 (01)
  • [47] Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2
    Verma, Sharad K.
    Tian, Xinrong
    LaFrance, Louis V.
    Duquenne, Celine
    Suarez, Dominic P.
    Newlander, Kenneth A.
    Romeril, Stuart P.
    Burgess, Joelle L.
    Grant, Seth W.
    Brackley, James A.
    Graves, Alan P.
    Scherzer, Daryl A.
    Shu, Art
    Thompson, Christine
    Ott, Heidi M.
    Van Aller, Glenn S.
    Machutta, Carl A.
    Diaz, Elsie
    Jiang, Yong
    Johnson, Neil W.
    Knight, Steven D.
    Kruger, Ryan G.
    McCabe, Michael T.
    Dhanak, Dashyant
    Tummino, Peter J.
    Creasy, Caretha L.
    Miller, William H.
    ACS MEDICINAL CHEMISTRY LETTERS, 2012, 3 (12): : 1091 - 1096
  • [48] The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type
    Wang, Yemin
    Chen, Shary Yuting
    Karnezis, Anthony N.
    Colborne, Shane
    Dos Santos, Nancy
    Lang, Jessica D.
    Hendricks, William P. D.
    Orlando, Krystal A.
    Yap, Damian
    Kommoss, Friedrich
    Bally, Marcel B.
    Morin, Gregg B.
    Trent, Jeffrey M.
    Weissman, Bernard E.
    Huntsman, David G.
    JOURNAL OF PATHOLOGY, 2017, 242 (03): : 371 - 383
  • [49] EZH2 Histone Methyltransferase and JMJD3 Histone Demethylase Implications in Prostate Cancer
    Idrissou, Mouhamed
    Daures, Marine
    Ben Jemia, Amani
    Judes, Gaelle
    Rifai, Khaldoun
    Penault-Llorca, Frederique
    Bignon, Yves-Jean
    Guy, Laurent
    Bernard-Gallon, Dominique
    OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, 2017, 21 (12) : 751 - 753
  • [50] Epigenetic regulation of cell adhesion and cell communication pathways by the histone methyltransferase Ezh2 in human endothelial cells
    Dreger, H.
    Meiners, S.
    Weller, A.
    Ludwig, A.
    Stangl, V.
    Baumann, G.
    Stangl, K.
    EUROPEAN HEART JOURNAL, 2011, 32 : 191 - 191
12345