To explore the effects of different traffic structures and wind speeds on concentration distribution of multi-component pollutants, CO, C4H8, and NO2 with proportions of 81%, 12%, and 7%, respectively, were selected for computational fluid dynamics simulations. Their concentrations were estimated in a reference scenario and five contrast scenarios. When the number of cars is reduced by 15%, their concentrations at point 1 (-28, 1.5) and point 2 (28, 1.5) will decrease by more than 10%. When the number of cars is reduced by 25%, their concentrations will decrease by 20%. The largest concentration in 1.5 m above the ground level under six scenarios is measured on the leeward side when x=-3.3 m. Even if the wind speed increases to 3.0 m/s, the position where the largest concentration occurs remains the same. When wind speed increased to 3.0 m/s, the pollutants concentration on the leeward side decreased by an average of 4%, whereas that on the windward side decreased by an average of 11%. An additional 3.2%, 3.4%, 3.4%, 2.8%, 3.3%, and 3.1% reduction in CO concentration on the leeward side occurred. These results can help to strengthen the policy-making to create a good travel environment for pedestrians.