The Heck reaction of electron-rich olefins with regiocontrol by hydrogen-bond donors

被引：108
|
作者：
Mo, Jun [1 ]
Xiao, Jianliang [1 ]
机构：
[1] Univ Liverpool, Dept Chem, Liverpool Ctr Mat & Catalysis, Liverpool L69 7ZD, Merseyside, England
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 25期
关键词：
Heck reaction; homogeneous catalysis; hydrogen bonding; ionic liquids; regioselectivity;
D O I：
10.1002/anie.200600799
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
No salt please: Halide scavengers AgOTf and TlOAc are not required for the Heck coupling of electron-rich olefins with aryl bromides and chlorides. Using ammonium additives, these reactions can be carried out in either an imidazolium ionic liquid or a common molecular solvent, thus furnishing 1,1′- disubstituted olefins in high yields with excellent regioselectivities. (Chemical Equation Presented). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：4152 / 4157
页数：6
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