miRNA regulation of cytokine genes

被引：130
|
作者：
Asirvatham, Ananthi J. [1 ]
Magner, William J. [1 ]
Tomasi, Thomas B. [1 ,2 ,3 ]
机构：
[1] Roswell Pk Canc Inst, Mol Med Lab, Dept Immunol, Buffalo, NY 14263 USA
[2] SUNY Buffalo, Sch Med & Biomed Sci, Dept Med, Buffalo, NY 14214 USA
[3] SUNY Buffalo, Sch Med & Biomed Sci, Dept Microbiol & Immunol, Buffalo, NY 14214 USA
来源：
CYTOKINE | 2009年 / 45卷 / 02期
关键词：
miRNA; ARE; Cytokine; Chemokine; Evolution; MESSENGER-RNA STABILITY; TUMOR-NECROSIS-FACTOR; TRANSFORMING-GROWTH-FACTOR; ACTIVATED PROTEIN-KINASE; AU-RICH ELEMENTS; NF-KAPPA-B; VIRUS-INDUCED LYMPHOMAS; TGF-BETA; POSTTRANSCRIPTIONAL REGULATION; HUMAN CANCER;
D O I：
10.1016/j.cyto.2008.11.010
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this review we discuss specific examples of regulation of cytokine genes and focus on a new mechanism involving post-transcriptional regulation via miRNAs. The post-transcriptional regulation of cytokine genes via the destabilizing activity of AU-rich elements [AREs] and miRNAs is a pre-requisite for regulating the half-life of many cytokines and achieving the temporal and spatial distributions required for regulation of these genes. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：58 / 69
页数：12
相关论文
共 50 条
  • [21] Comparison of miRNA-101a-3p and miRNA-144a-3p regulation with the key genes of alpaca melanocyte pigmentation
    Zhu, Zhiwei
    Ma, Yueyue
    Li, Yuan
    Cheng, Zhixue
    Li, Huifeng
    Zhang, Lihuan
    Xu, Dongmei
    Li, Pengfei
    BMC MOLECULAR BIOLOGY, 2019, 20 (01):
  • [22] Methylation of miRNA genes and oncogenesis
    V. I. Loginov
    S. V. Rykov
    M. V. Fridman
    E. A. Braga
    Biochemistry (Moscow), 2015, 80 : 145 - 162
  • [23] Methylation of miRNA genes and oncogenesis
    Loginov, V. I.
    Rykov, S. V.
    Fridman, M. V.
    Braga, E. A.
    BIOCHEMISTRY-MOSCOW, 2015, 80 (02) : 145 - 162
  • [24] Expression of Arabidopsis MIRNA genes
    Xie, ZX
    Allen, E
    Fahlgren, N
    Calamar, A
    Givan, SA
    Carrington, JC
    PLANT PHYSIOLOGY, 2005, 138 (04) : 2145 - 2154
  • [25] Distinguishing cytokine and miRNA signatures in neonatal encephalopathy
    不详
    PEDIATRIC RESEARCH, 2021, 89 (03) : 393 - 393
  • [26] Fish cytokine genes
    Secombes, CJ
    Zou, J
    Collet, B
    AQUATIC GENOMIC: STEPS TOWARD A GREAT FUTURE, 2003, : 277 - 285
  • [27] Rainbow trout cytokine and cytokine receptor genes
    Secombes, C
    Zou, J
    Daniels, G
    Cunningham, C
    Koussounadis, A
    Kemp, G
    IMMUNOLOGICAL REVIEWS, 1998, 166 : 333 - 340
  • [28] Cytokine genes in fish
    Secombes, CJ
    Zou, J
    Laing, K
    Daniels, GD
    Cunningham, C
    AQUACULTURE, 1999, 172 (1-2) : 93 - 102
  • [29] CYTOKINE AND CYTOKINE RECEPTOR GENES CAPTURED BY VIRUSES
    SPRIGGS, MK
    CURRENT OPINION IN IMMUNOLOGY, 1994, 6 (04) : 526 - 529
  • [30] Allele specific regulation of cytokine genes: Monoallelic expression of the IL-1A gene
    Verweij, CL
    Bayley, JP
    Bakker, A
    Kaijzel, EL
    PROGRESS IN BASIC AND CLINICAL IMMUNOLOGY, 2001, 495 : 129 - 139
12345