Synthesis of new trifluoromethylated indole derivatives

被引：30
|
作者：
Darehkordi, Ali [1 ]
Rahmani, Fariba [1 ]
Hashemi, Vahide [1 ]
机构：
[1] Vali E Asr Univ Rafsanjan, Fac Sci, Dept Chem, Rafsanjan 77176, Iran
来源：
TETRAHEDRON LETTERS | 2013年 / 54卷 / 35期
关键词：
Trifluoromethylated indole; 2,2,2-Trifluoro-N-arylacetimidoyl chloride; Indole;
D O I：
10.1016/j.tetlet.2013.06.093
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New indole trifluoromethyl derivatives have been synthesized using the reaction of indole derivatives with different 2,2,2-trifluoro-N-arylacetimidoyl chlorides in the presence of NaH as a base in acetonitrile at room temperature under an N-2 atmosphere. The FT-IR, F-19 NMR, H-1 NMR, C-13 NMR, COSY and HMBC spectra and elemental analysis confirm the structures of the products. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4689 / 4692
页数：4
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