A Simple and Efficient One-Pot Synthesis of Spirooxindoles in Water Under Microwave Irradiation Conditions

被引：8
|
作者：
Zhu, Song-Lei [1 ,2 ]
Ji, Shun-Jun [1 ]
Zhao, Kai [1 ]
Zhang, Yong [1 ]
机构：
[1] Suzhou Soochow Univ, Coll Chem & Chem Engn, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China
[2] Xuzhou Med Coll, Dept Chem, Xuzhou 221002, Peoples R China
来源：
LETTERS IN ORGANIC CHEMISTRY | 2008年 / 5卷 / 04期
基金：
中国国家自然科学基金;
关键词：
Spirooxindoles; three-component synthesis; microwave irradiation; aqueous media;
D O I：
10.2174/157017808784049489
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient method for the synthesis of spirooxindoles derivatives by one-pot reactions of isatins, activated methylene reagents and activated carbonyl compounds in water under microwave irradiation was reported. This protocol has the advantages of short reaction time, high yields, easy work-up procedure and environmentally benign characters.
引用
收藏
页码：319 / 323
页数：5
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