Advancing the Science of Developmental Neurotoxicity (DNT): Testing for Better Safety Evaluation

被引：82

作者：

Bal-Price, Anna K. ^{[1
]}

Coecke, Sandra ^{[1
]}

Costa, Lucio ^{[2
]}

Crofton, Kevin M. ^{[3
]}

Fritsche, Ellen ^{[4
,5
]}

Goldberg, Alan ^{[6
]}

Grandjean, Philippe ^{[7
]}

Lein, Pamela J. ^{[8
]}

Li, Abby ^{[9
]}

Lucchini, Roberto ^{[10
]}

Mundy, William R. ^{[3
]}

Padilla, Stephanie ^{[3
]}

Persico, Antonio M. ^{[11
,12
]}

Seiler, Andrea E. M. ^{[13
]}

Kreysa, Joachim ^{[1
]}

机构：

[1] EC Joint Res Ctr, Inst Hlth & Consumer Protect, Validat Alternat Methods Unit, I-21027 Ispra, VA, Italy

[2] Univ Washington, Dept Environm & Occupat Hlth Sci, Seattle, WA 98195 USA

[3] US EPA, Integrated Syst Toxicol Div, Res Triangle Pk, NC 27711 USA

[4] IUF Leibniz Res Inst Environm Med, Dusseldorf, Germany

[5] Rhein Westfal TH Aachen, Aachen, Germany

[6] Johns Hopkins Univ, CAAT, Baltimore, MD USA

[7] Univ So Denmark, Dept Environm Med, Inst Publ Hlth, Odense, Denmark

[8] Univ Calif Davis, Ctr Childrens Environm Hlth, Davis, CA 95616 USA

[9] Exponent Hlth Sci, San Francisco, CA USA

[10] Univ Brescia, Sect Occupat Hlth & Ind Hyg, Dept Expt & Appl Med, I-25121 Brescia, Italy

[11] Univ Campus Biomed, Rome, Italy

[12] IRCCS Fdn Santa Lucia, Rome, Italy

[13] ZEBET Alternat Methods Anim Expt, Fed Inst Risk Assessment BfR, Berlin, Germany

来源：

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION | 2012年 / 29卷 / 02期

关键词：

NEURAL PROGENITOR CELLS; CENTRAL-NERVOUS-SYSTEM; UMBILICAL-CORD BLOOD; ENVIRONMENTAL-FACTORS; ALTERNATIVE METHODS; NEURITE OUTGROWTH; PARKINSON-DISEASE; LEAD-EXPOSURE; AUTISM; TOXICITY;

D O I：

10.14573/altex.2012.2.202

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：202 / 215

页数：14

共 50 条

[31] Developmental neurotoxicity (DNT) of contaminants of emerging concern (CECs) in the zebrafish (Danio rerio)
Nilsen, S.
Pedersen, B. Bergquist
Hage-Ahmad, S.
Lobert, V. H.
Myhre, O.
Lyche, J. L.
Hurem, S.
TOXICOLOGY LETTERS, 2024, 399 : S185 - S185
[32] Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods
Bal-Price, Anna
Pistollato, Francesca
Sachana, Magdalini
Bopp, Stephanie K.
Munn, Sharon
Worth, Andrew
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 354 : 7 - 18
[33] Conversion of Developmental Neurotoxicity (DNT) information into a structure-searchable relational database
Acuff, Karen
Broening, Bill
Crofton, Kevin
Fix, Andrew
Julien, Elizabeth
Nash, Jay
Richard, Ann
Tozer, Sarah
Yang, Chihae
NEUROTOXICOLOGY AND TERATOLOGY, 2008, 30 (03) : 252 - 252
[34] Integrated testing strategies for developmental neurotoxicity testing
Behl, M.
Ryan, K.
Hsieh, J-H
Parham, F.
Shapiro, A.
Collins, B.
Sipes, N.
Birnbaum, L. S.
Bucher, J. R.
Walker, N.
Paules, R. S.
NEUROTOXICOLOGY AND TERATOLOGY, 2019, 73 : 85 - 85
[35] Integrated Testing Strategies for Developmental Neurotoxicity Testing
Behl, M.
Ryan, K.
Hsieh, J-H
Parham, F.
Shapiro, A.
Collins, B.
Sipes, N.
Birnbaum, L. S.
Bucher, J. R.
Walker, N.
Paules, R. S.
BIRTH DEFECTS RESEARCH, 2019, 111 (09): : 466 - 466
[36] Brain MPS for developmental neurotoxicity testing
Smirnova, L.
TOXICOLOGY LETTERS, 2024, 399 : S39 - S39
[37] Developmental neurotoxicity testing: A path forward
Crofton, Kevin M.
Mundy, William R.
Shafer, Timothy J.
CONGENITAL ANOMALIES, 2012, 52 (03) : 140 - 146
[38] Organoid intelligence for developmental neurotoxicity testing
El Din, Dowlette-Mary Alam
Shin, Jeongwon
Lysinger, Alexandra
Roos, Matthew J.
Johnson, Erik C.
Shafer, Timothy J.
Hartung, Thomas
Smirnova, Lena
FRONTIERS IN CELLULAR NEUROSCIENCE, 2024, 18
[39] Zebrafish as a model for developmental neurotoxicity testing
Ton, Christopher
Lin, Yingxin
Willett, Catherine
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 2006, 76 (07) : 553 - 567
[40] Evaluating the developmental neurotoxicity (DNT) potential of chemicals in an in vitro model based on human neurospheres
Rockel, Thomas
Abel, Josef
Fritsche, Ellen
TOXICOLOGY LETTERS, 2009, 189 : S144 - S144

← 1 2 3 4 5 →