REMIMAZOLAM GABAA Benzodiazepine Site Receptor Agonist Anesthetic/Sedative

被引：1
|
作者：
Piehl, Estee [1 ]
机构：
[1] Univ Colorado Denver, Dept Anesthesiol, Aurora, CO 80045 USA
来源：
DRUGS OF THE FUTURE | 2013年 / 38卷 / 09期
关键词：
Anesthetic; Benzodiazepine; Sedation; Remimazolam; CNS-7056; CNS; 7056; MIDAZOLAM; PHARMACOKINETICS; PHARMACODYNAMICS; CNS-7056; EFFICACY; SAFETY;
D O I：
10.1358/dof.2013.038.09.1990154
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Remimazolam, also known as CNS-7056, is a novel, ultra-short-acting benzodiazepine. It has a faster onset and shorter duration of action than midazolam, with reliable metabolism to an inactive metabolite, CNS-7054, by plasma esterases. The sedative effects appear typical of benzodiazepines and are dependent on dose, with a wide therapeutic range.
引用
收藏
页码：625 / 630
页数：6
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