Orexin receptor antagonists and insomnia treatment: state of the art

被引:0
|
作者
Gotter, A. L. [1 ]
Coleman, P. J. [2 ]
Kuduk, S. D. [2 ]
Tannenbaum, P. L. [1 ]
Struyk, A. [3 ]
Wrishko, R. E. [4 ]
Connor, K. M. [5 ]
Herring, W. J. [5 ]
Renger, J. J. [1 ]
Winrow, C. J. [1 ]
机构
[1] Merck Res Labs, Dept Neurosci, West Point, PA USA
[2] Merck Res Labs, Dept Med Chem, West Point, PA USA
[3] Merck Res Labs, Dept Clin Pharmacol & Expt Therapeut, West Point, PA USA
[4] Merck Res Labs, Dept Pharmacokinet & Drug Metab, West Point, PA USA
[5] Merck Res Labs, Dept Clin Res, West Point, PA USA
关键词
D O I
10.1016/S0924-977X(14)70211-1
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
S.27.02
引用
收藏
页码:S144 / S145
页数:2
相关论文
共 50 条
  • [21] An Update on Dual Orexin Receptor Antagonists and Their Potential Role in Insomnia Therapeutics
    Janto, Kayla
    Prichard, J. Roxanne
    Pusalavidyasagar, Snigdha
    JOURNAL OF CLINICAL SLEEP MEDICINE, 2018, 14 (08): : 1399 - 1408
  • [22] Almorexant, a dual orexin receptor antagonist for the treatment of insomnia
    Neubauer, David N.
    CURRENT OPINION IN INVESTIGATIONAL DRUGS, 2010, 11 (01) : 101 - 110
  • [23] A look at the orexin receptor antagonism approach for the treatment of insomnia
    Balasubramaniam, M.
    Farheen, S. A.
    Srinivas, S.
    Tampi, R. R.
    DRUGS OF THE FUTURE, 2019, 44 (07) : 535 - 544
  • [24] Lemborexant Dual orexin receptor antagonist Treatment of insomnia
    Hoyer, D.
    Jacobson, L. H.
    DRUGS OF THE FUTURE, 2018, 43 (10) : 715 - 730
  • [25] Orexin receptor antagonists
    Christopher, John A.
    PHARMACEUTICAL PATENT ANALYST, 2012, 1 (03) : 329 - 346
  • [26] New pharmacological strategies for the management of insomnia : Suvorexant, one receptor antagonists orexin
    Salin-Pascual, Rafael J.
    REVISTA MEXICANA DE NEUROCIENCIA, 2016, 17 (06): : 97 - 105
  • [27] Orexin Receptor Antagonists
    Hoyer D.
    Jacobson L.H.
    Current Sleep Medicine Reports, 2017, 3 (4) : 342 - 353
  • [28] Selective orexin receptor antagonists for the treatment of CNS disorders
    Shireman, Brock T.
    Letavic, Michael A.
    Bonaventure, Pascal
    Branstetter, Bryan
    Dugovic, Christine
    Hack, Michael
    Lord, Brian
    Ly, Kiev S.
    Morton, Kirsten L.
    Rudolph, Dale A.
    Savall, Brad M.
    Shah, Chandra
    Shelton, Jonathan
    Shoblock, James
    Nepomuceno, Diane
    Lovenberg, Timothy W.
    Carruthers, Nicholas I.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [29] Dual orexin receptor antagonists for insomnia in youth with neurodevelopmental disorders: a case series and review
    Besterman, Aaron D.
    Jeste, Shafali S.
    EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 2023, 32 (03) : 527 - 531
  • [30] Dual orexin receptor antagonists for insomnia in youth with neurodevelopmental disorders: a case series and review
    Aaron D. Besterman
    Shafali S. Jeste
    European Child & Adolescent Psychiatry, 2023, 32 : 527 - 531