Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout

被引:74
|
作者
Bursill, David [1 ,2 ]
Taylor, William J. [3 ,4 ]
Terkeltaub, Robert [5 ,6 ]
Kuwabara, Masanari [7 ,8 ]
Merriman, Tony R. [9 ]
Grainger, Rebecca [3 ,4 ]
Pineda, Carlos [10 ]
Louthrenoo, Worawit [11 ]
Edwards, N. Lawrence [12 ]
Andres, Mariano [13 ,14 ]
Vargas-Santos, Ana Beatriz [15 ]
Roddy, Edward [16 ]
Pascart, Tristan [17 ,18 ]
Lin, Ching-Tsai [19 ]
Perez-Ruiz, Fernando [20 ,21 ,22 ]
Tedeschi, Sara K. [23 ,24 ]
Kim, Seoyoung C. [23 ,24 ]
Harrold, Leslie R. [25 ,26 ]
McCarthy, Geraldine [27 ,28 ]
Kumar, Nitin [29 ]
Chapman, PeterT. [30 ]
Tausche, Anne-Kathrin [31 ]
Vazquez-Mellado, Janitzia [32 ,33 ]
Gutierrez, Marwin [34 ]
Castelar-Pinheiro, Geraldo da Rocha [15 ]
Richette, Pascal [35 ,36 ,37 ]
Pascual, Eliseo [13 ,14 ]
Fisher, Mark C. [23 ,38 ]
Burgos-Vargas, Ruben [32 ,33 ]
Robinson, Philip C. [39 ,40 ]
Singh, Jasvinder A. [41 ,42 ]
Jansen, Tim L. [43 ]
Saag, Kenneth G. [42 ]
Slot, Ole [44 ]
Uhlig, Tillmann [45 ]
Solomon, Daniel H. [23 ,24 ]
Keenan, Robert T. [46 ]
Scire, Carlo Alberto [47 ,48 ]
Biernat-Kaluza, Edyta [49 ]
Dehlin, Mats [50 ]
Nuki, George [51 ]
Schlesinger, Naomi [52 ]
Janssen, Matthijs [43 ]
Stamp, Lisa K. [53 ]
Sivera, Francisca [54 ]
Reginato, Anthony M. [55 ]
Jacobsson, Lennart [50 ]
Liote, Frederic [35 ,36 ,37 ]
Ea, Hang-Korng [35 ,36 ,37 ]
Rosenthal, Ann [56 ,57 ]
机构
[1] Univ Auckland, Auckland, New Zealand
[2] Univ Adelaide, Adelaide Med Sch, Adelaide, SA, Australia
[3] Univ Otago, Wellington, New Zealand
[4] Hutt Valley Dist Hlth Board, Lower Hutt, New Zealand
[5] Vet Affairs Med Ctr, San Diego, CA 92161 USA
[6] Univ Calif San Diego, San Diego, CA 92103 USA
[7] Toranomon Gen Hosp, Tokyo, Japan
[8] Univ Colorado, Aurora, CO USA
[9] Univ Otago, Dunedin, New Zealand
[10] Inst Nacl Rehabil Luis Guillermo Ibarra Ibarra, Mexico City, DF, Mexico
[11] Chiang Mai Univ, Chiang Mai, Thailand
[12] Univ Florida, Coll Med, Gainesville, FL USA
[13] Hosp Univ Alicante, Alicante, Spain
[14] Univ Miguel Hernandez, Alicante, Spain
[15] Univ Estado Rio De Janeiro, Rio De Janeiro, Brazil
[16] Keele Univ, Keele, Staffs, England
[17] Lille Catholic Univ, Lomme Les Lille, France
[18] St Philibert Hosp, Lomme Les Lille, France
[19] Taichung Vet Gen Hosp, Taichung, Taiwan
[20] Univ Basque Country, Biscay, Spain
[21] Cruces Univ Hosp, Baracaldo, Spain
[22] Biocruces Hlth Res Inst, Baracaldo, Spain
[23] Harvard Med Sch, Boston, MA 02115 USA
[24] Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA
[25] Corrona LLC, Waltham, MA USA
[26] Univ Massachusetts, Med Sch, Worcester, MA USA
[27] Mater Misericordiae Univ Hosp, Dublin, Ireland
[28] Univ Coll, Dublin, Ireland
[29] Henry Ford Hosp, Detroit, MI 48202 USA
[30] Christchurch Hosp, Christchurch, New Zealand
[31] Tech Univ Dresden, Univ Hosp Carl Gustav Carus, Dresden, Germany
[32] Hosp Gen Mexico City, Mexico City, DF, Mexico
[33] Univ Nacl Autonoma Mexico, Mexico City, DF, Mexico
[34] Inst Nacl Rehabil, Mexico City, DF, Mexico
[35] Hop Lariboisiere, AP HP, Paris, France
[36] INSERM, UMR 1132, Paris, France
[37] Univ Paris Diderot, Paris, France
[38] Massachusetts Gen Hosp, Boston, MA 02114 USA
[39] Univ Queensland, Sch Med, Herston, Qld, Australia
[40] Royal Brisbane & Womens Hosp, Herston, Qld, Australia
[41] Vet Affairs Med Ctr, Birmingham, AL USA
[42] Univ Alabama Birmingham, Birmingham, AL USA
[43] Viecuri Med Ctr, Venlo, Netherlands
[44] Rigshosp Glostrup, Glostrup, Denmark
[45] Diakonhjemmet Hosp, Oslo, Norway
[46] Duke Univ, Sch Med, Durham, NC USA
[47] Univ Ferrara, Ferrara, Italy
[48] Italian Soc Rheumatol, Milan, Italy
[49] ORLIK, Warsaw, Poland
[50] Univ Gothenburg, Sahlgrenska Acad, Gothenburg, Sweden
关键词
D O I
10.1002/acr.23607
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective The language currently used to describe gout lacks standardization. The aim of this project was to develop a consensus statement on the labels and definitions used to describe the basic disease elements of gout. Methods Experts in gout (n = 130) were invited to participate in a Delphi exercise and face-to-face consensus meeting to reach consensus on the labeling and definitions for the basic disease elements of gout. Disease elements and labels in current use were derived from a content analysis of the contemporary medical literature, and the results of this analysis were used for item selection in the Delphi exercise and face-to-face consensus meeting. Results There were 51 respondents to the Delphi exercise and 30 attendees at the face-to-face meeting. Consensus agreement (>= 80%) was achieved for the labels of 8 disease elements through the Delphi exercise; the remaining 3 labels reached consensus agreement through the face-to-face consensus meeting. The agreed labels were monosodium urate crystals, urate, hyperuric(a)emia, tophus, subcutaneous tophus, gout flare, intercritical gout, chronic gouty arthritis, imaging evidence of monosodium urate crystal deposition, gouty bone erosion, and podagra. Participants at the face-to-face meeting achieved consensus agreement for the definitions of all 11 elements and a recommendation that the label "chronic gout" should not be used. Conclusion Consensus agreement was achieved for the labels and definitions of 11 elements representing the fundamental components of gout etiology, pathophysiology, and clinical presentation. The Gout, Hyperuricemia, and Crystal-Associated Disease Network recommends the use of these labels when describing the basic disease elements of gout.
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页码:427 / 434
页数:8
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