A facile synthesis of 3-substituted pipecolic acids, chimeric amino acids

被引:20
|
作者
Makara, GM [1 ]
Marshall, GR [1 ]
机构
[1] WASHINGTON UNIV,SCH MED,DEPT MOL BIOL & PHARMACOL,ST LOUIS,MO 63110
关键词
D O I
10.1016/S0040-4039(97)01128-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Three protected 3-substituted pipecolic acid analogs were prepared as constrained chimeric amino acid building blocks. The concise synthetic route enables the synthesis of other derivatives with sidechain functionality of amino acids as well. (C) 1997 Elsevier Science Ltd.
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页码:5069 / 5072
页数:4
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