Synthesis and design of biologically inspired biocompatible iron oxide nanoparticles for biomedical applications

被引：112
|
作者：
Demirer, Gozde S. [1 ]
Okur, Aysu C. [2 ]
Kizilel, Seda [1 ,2 ]
机构：
[1] Koc Univ, Chem & Biol Engn, TR-34450 Istanbul, Turkey
[2] Koc Univ, Biomed Sci & Engn, TR-34450 Istanbul, Turkey
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2015年 / 3卷 / 40期
关键词：
MAGNETIC NANOPARTICLES; CONTRAST AGENTS; IN-VIVO; GENE-THERAPY; SUPERPARAMAGNETIC NANOPARTICLES; DRUG-DELIVERY; FE3O4; NANOPARTICLES; PHOTOACOUSTIC TOMOGRAPHY; HYDROTHERMAL SYNTHESIS; SURFACE MODIFICATION;
D O I：
10.1039/c5tb00931f
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
During the last couple of decades considerable research efforts have been directed towards the synthesis and coating of iron oxide nanoparticles (IONPs) for biomedical applications. To address the current limitations, recent studies have focused on the design of new generation nanoparticle systems whose internalization and targeting capabilities have been improved through surface modifications. This review covers the most recent challenges and advances in the development of IONPs with enhanced quality, and biocompatibility for various applications in biotechnology and medicine.
引用
收藏
页码：7831 / 7849
页数：19
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