Characterization of FASN-selective small-molecule inhibitors in preclinical tumor models

被引:0
|
作者
Heuer, Timothy S. [1 ]
Chen, Minchao [1 ]
Ventura, Richard [1 ]
Waszczuk, Joanna [1 ]
Yendluri, Satya [1 ]
Lai, Julie [1 ]
Tep, Samnang [1 ]
Feng, Shirley [1 ]
Johnson, Russell [1 ]
Zaharia, Cristiana [1 ]
Buckley, Douglas [1 ]
Kemble, George [1 ]
机构
[1] 3V Biosci, Menlo Pk, CA USA
关键词
D O I
10.1158/1535-7163.TARG-13-B261
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
B261
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Small-molecule arginase inhibitors
    Ivanenkov, Yan A.
    Chufarova, Nina V.
    PHARMACEUTICAL PATENT ANALYST, 2014, 3 (01) : 65 - 85
  • [22] Small-molecule enzyme inhibitors
    Edwards, P
    DRUG DISCOVERY TODAY, 2001, 6 (03) : 160 - 160
  • [23] Selective and potent small-molecule inhibitors of PI3Ks
    Jeong, Yujeong
    Kwon, Daeil
    Hong, Sungwoo
    FUTURE MEDICINAL CHEMISTRY, 2014, 6 (07) : 737 - 756
  • [24] Preclinical anti-tumor activity of small-molecule oral PD-L1 checkpoint inhibitors.
    Thi, Emily P.
    Cole, Andrew G.
    Heffernan, Gavin
    Iott, Christina L.
    Ozturk, Seyma
    Ganchua, Sharie C.
    Nguyen, Dan
    Graves, Ingrid
    Quintero, Jorge G.
    Stever, Kim
    Fan, Kristi
    Ahuja, Vijay
    Kultgen, Steven G.
    Shubina, Maria
    Liu, Boya
    Tang, Sunny
    Harasym, Troy
    Lam, Angela M.
    Sofia, Michael J.
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [25] Small-molecule inhibitors of Bcl-2 for tumor cells death?
    Juin, P
    M S-MEDECINE SCIENCES, 2001, 17 (05): : 655 - 656
  • [26] Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
    Han, Huiying
    Jain, Atul D.
    Truica, Mihai I.
    Izquierdo-Ferrer, Javier
    Anker, Jonathan F.
    Lysy, Barbara
    Sagar, Vinay
    Luan, Yi
    Chalmers, Zachary R.
    Unno, Kenji
    Mok, Hanlin
    Vatapalli, Rajita
    Yoo, Young A.
    Rodriguez, Yara
    Kandela, Irawati
    Parker, J. Brandon
    Chakravarti, Debabrata
    Mishra, Rama K.
    Schiltz, Gary E.
    Abdulkadir, Sarki A.
    CANCER CELL, 2019, 36 (05) : 483 - +
  • [27] Small-molecule inhibitors of carboxylesterase Notum
    Zhao, Yuguang
    Jolly, Sarah
    Benvegnu, Stefano
    Jones, E. Yvonne
    Fish, Paul, V
    FUTURE MEDICINAL CHEMISTRY, 2021, 13 (11) : 1001 - 1015
  • [28] Probing Translation with Small-Molecule Inhibitors
    Blanchard, Scott C.
    Cooperman, Barry S.
    Wilson, Daniel N.
    CHEMISTRY & BIOLOGY, 2010, 17 (06): : 633 - 645
  • [29] Discovery of small-molecule inhibitors of tyrosinase
    Germanas, Juris P.
    Wang, Shugauang
    Miner, Andrew
    Hao, Wayne
    Ready, Joseph M.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (24) : 6871 - 6875
  • [30] Small-molecule allosteric inhibitors of BAX
    Thomas P. Garner
    Dulguun Amgalan
    Denis E. Reyna
    Sheng Li
    Richard N. Kitsis
    Evripidis Gavathiotis
    Nature Chemical Biology, 2019, 15 : 322 - 330