Diabetes is associated with drug-resistant tuberculosis in Eastern Taiwan

被引：28

作者：

Hsu, A-H. ^{[1
,2
]}

Lee, J-J. ^{[1
]}

Chiang, C-Y. ^{[3
,4
,5
]}

Li, Y-H. ^{[6
]}

Chen, L-K. ^{[2
,7
]}

Lin, C-B. ^{[1
]}

机构：

[1] Tzu Chi Univ, Tzu Chi Gen Hosp, Dept Internal Med, Hualien, Taiwan

[2] Tzu Chi Univ, Inst Med Sci, Hualien, Taiwan

[3] Int Union TB & Lung Dis, Paris, France

[4] Taipei Med Univ, Wan Fang Hosp, Dept Internal Med, Div Pulm Med, Taipei, Taiwan

[5] Taipei Med Univ, Coll Med, Sch Med, Dept Internal Med, Taipei, Taiwan

[6] Tzu Chi Univ, Dept Publ Hlth, Hualien, Taiwan

[7] Tzu Chi Gen Hosp, Dept Clin Pathol, Hualien, Taiwan

来源：

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | 2013年 / 17卷 / 03期

关键词：

diabetes; isoniazid resistance; transmission; multidrug-resistant tuberculosis;

D O I：

10.5588/ijtld.11.0670

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We assessed the association between diabetes mellitus and drug-resistant tuberculosis (TB). Among new patients, diabetes was significantly associated with any resistance to isoniazid excluding multidrug-resistant TB (MDR-TB; adjusted OR [aOR] 1.88, 95%CI 1.07-3.31), but not with MDR-TB (aOR 0.95, 95%CI 0.34-2.68). Among previously treated patients, diabetes was also significantly associated with INH resistance (aOR 6.76, 95%CI 1.53-29.98) but not with MDR-TB (aOR 1.52, 95%CI 0.59-3.95). We concluded that diabetes was associated with INH resistance and speculated that the sample size of retreatment cases was insufficient to confirm the association between diabetes and MDR-TB.

引用

页码：354 / 356

页数：3

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