Diabetes is associated with drug-resistant tuberculosis in Eastern Taiwan

被引:28
|
作者
Hsu, A-H. [1 ,2 ]
Lee, J-J. [1 ]
Chiang, C-Y. [3 ,4 ,5 ]
Li, Y-H. [6 ]
Chen, L-K. [2 ,7 ]
Lin, C-B. [1 ]
机构
[1] Tzu Chi Univ, Tzu Chi Gen Hosp, Dept Internal Med, Hualien, Taiwan
[2] Tzu Chi Univ, Inst Med Sci, Hualien, Taiwan
[3] Int Union TB & Lung Dis, Paris, France
[4] Taipei Med Univ, Wan Fang Hosp, Dept Internal Med, Div Pulm Med, Taipei, Taiwan
[5] Taipei Med Univ, Coll Med, Sch Med, Dept Internal Med, Taipei, Taiwan
[6] Tzu Chi Univ, Dept Publ Hlth, Hualien, Taiwan
[7] Tzu Chi Gen Hosp, Dept Clin Pathol, Hualien, Taiwan
关键词
diabetes; isoniazid resistance; transmission; multidrug-resistant tuberculosis;
D O I
10.5588/ijtld.11.0670
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We assessed the association between diabetes mellitus and drug-resistant tuberculosis (TB). Among new patients, diabetes was significantly associated with any resistance to isoniazid excluding multidrug-resistant TB (MDR-TB; adjusted OR [aOR] 1.88, 95%CI 1.07-3.31), but not with MDR-TB (aOR 0.95, 95%CI 0.34-2.68). Among previously treated patients, diabetes was also significantly associated with INH resistance (aOR 6.76, 95%CI 1.53-29.98) but not with MDR-TB (aOR 1.52, 95%CI 0.59-3.95). We concluded that diabetes was associated with INH resistance and speculated that the sample size of retreatment cases was insufficient to confirm the association between diabetes and MDR-TB.
引用
收藏
页码:354 / 356
页数:3
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