Construction of a transparent mutant of human purine nucleoside phosphorylase for the purposes of probing the catalytic loop region

被引：0
|
作者：
Wing, Corin
Zaslavsky, Dimitry
Schramm, Vern L.
机构：
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 230卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
263-BIOL
引用
收藏
页码：U627 / U628
页数：2
相关论文
共 50 条
  • [21] Structures of human purine nucleoside phosphorylase complexed with inosine and ddI
    Canduri, F
    dos Santos, DM
    Silva, RG
    Mendes, MA
    Basso, LA
    Palma, MS
    de Azevedo, WF
    Santos, DS
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 313 (04) : 907 - 914
  • [22] Crystal structure of human purine nucleoside phosphorylase at 2.3 Å resolution
    de Azevedo, WF
    Canduri, F
    dos Santos, DM
    Silva, RG
    de Oliveira, JS
    de Carvalho, LPS
    Basso, LA
    Mendes, MA
    Palma, MS
    Santos, DS
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 308 (03) : 545 - 552
  • [23] INTRON REQUIREMENT FOR EXPRESSION OF THE HUMAN PURINE NUCLEOSIDE PHOSPHORYLASE GENE
    JONSSON, JJ
    FORESMAN, MD
    WILSON, N
    MCIVOR, RS
    NUCLEIC ACIDS RESEARCH, 1992, 20 (12) : 3191 - 3198
  • [24] Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir
    dos Santos, DM
    Canduri, F
    Pereira, JH
    Dias, MVB
    Silva, RG
    Mendes, MA
    Palma, MS
    Basso, LA
    de Azevedo, WF
    Santos, DS
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 308 (03) : 553 - 559
  • [25] Computer Simulations Reveal Substrate Specificity of Glycosidic Bond Cleavage in Native and Mutant Human Purine Nucleoside Phosphorylase
    Isaksen, Geir Villy
    Hopmann, Kathrin Helen
    Aqvist, Johan
    Brandsdal, Bjorn Olav
    BIOCHEMISTRY, 2016, 55 (14) : 2153 - 2162
  • [26] Catalytic mechanism and inhibition studies of purine nucleoside phosphorylase (PNP) in Micrococcus luteus
    Choi, HS
    JOURNAL OF MICROBIOLOGY, 1997, 35 (01) : 15 - 20
  • [27] BOVINE BRAIN PURINE-NUCLEOSIDE PHOSPHORYLASE PURIFICATION, CHARACTERIZATION, AND CATALYTIC MECHANISM
    LEWIS, AS
    GLANTZ, MD
    BIOCHEMISTRY, 1976, 15 (20) : 4451 - 4457
  • [28] HUMAN ERYTHROCYTIC PURINE NUCLEOSIDE PHOSPHORYLASE - REACTION WITH SUGAR-MODIFIED NUCLEOSIDE SUBSTRATES
    STOECKLER, JD
    CAMBOR, C
    PARKS, RE
    BIOCHEMISTRY, 1980, 19 (01) : 102 - 107
  • [29] Catalytic-site design for inverse heavy-enzyme isotope effects in human purine nucleoside phosphorylase
    Harijan, Rajesh K.
    Zoi, Ioanna
    Antoniou, Dimitri
    Schwartz, Steven D.
    Schramm, Vern L.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (25) : 6456 - 6461
  • [30] Design and evaluation of 5′-modified nucleoside analogs as prodrugs for an E. coli purine nucleoside phosphorylase mutant
    Parker, WB
    Allan, PW
    Ealick, SE
    Sorscher, EJ
    Hassan, AEA
    Silamkoti, AV
    Fowler, AT
    Waud, WR
    Secrist, JA
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2005, 24 (5-7): : 387 - 392
12345