Gold-catalyzed formation of aryl-fused pyrazolooxazepines via intramolecular regioselective 7-exo-dig cyclization

被引：7

作者：

Guduru, Ravinder ^{[1
,2
]}

Mangina, N. S. V. M. Rao ^{[1
,2
]}

Sridhar, Balasubramanian ^{[3
]}

Karunakar, Galla V. ^{[1
,2
]}

机构：

[1] Indian Inst Chem Technol, CSIR, Div Fluoro & Agrochem, Hyderabad 500007, Andhra Pradesh, India

[2] Acad Sci & Innovat Res, Ghaziabad 201002, India

[3] Indian Inst Chem Technol, CSIR, Ctr Xray Crystallog, Hyderabad 500007, Andhra Pradesh, India

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2019年 / 17卷 / 10期

关键词：

PROPARGYLIC BETA-ENAMINONES; 3-COMPONENT SYNTHESIS; ONE-POT; RINGS; AMINO;

D O I：

10.1039/c8ob03157f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient method was developed for the synthesis of substituted aryl-fused pyrazolooxazepines from ortho-O-propargyl aryl pyrazoles by gold catalysis. In this organic transformation a new C-N bond was formed regioselectively via 7-exo-dig cyclization. Moderate to good yields of aryl-fused pyrazolooxazepine derivatives were obtained with significant molecular complexity in one-pot.

引用

页码：2809 / 2817

页数：9

共 40 条

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