Clinical Characteristics and Overall Survival Among Acute Myeloid Leukemia (AML) Patients with TP53 Gene Mutation (TP53m) or Chromosome 17p Deletion (17p del)

被引:1
|
作者
Daver, Naval [1 ]
Iqbal, Shahed [2 ]
Huang, Julie [2 ]
Renard, Camille [2 ]
Lin, Joyce [2 ]
Pan, Harry [2 ]
Xing, Guan [2 ]
Pan, Yang [2 ]
Ramsingh, Giri [2 ]
机构
[1] MD Anderson Canc Ctr, Houston, TX USA
[2] Gilead Sci Inc, 353 Lakeside Dr, Foster City, CA 94404 USA
关键词
D O I
10.1182/blood-2022-170298
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1445 / 1446
页数:2
相关论文
共 50 条
  • [21] Aberrant Nuclear p53 Expression Predicts Hemizygous 17p (TP53) Deletion in Chronic Lymphocytic Leukemia
    Chang, Hong
    Jiang, Allan M.
    Qi, Connie X. Y.
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2010, 133 (01) : 70 - 74
  • [22] The gene expression signature associated with TP53 mutation/deletion in chronic lymphocytic leukaemia is dominated by the under-expression of TP53 and other genes on chromosome 17p
    Lin, Ke
    Lane, Brian
    Carter, Anthony
    Johnson, Gillian G.
    Onwuazor, Obiageli
    Oates, Melanie
    Zenz, Thorsten
    Stilgenbauer, Stephan
    Atherton, Mark
    Douglas, Angela
    Ebrahimi, Bahram
    Sherrington, Paul D.
    Pettitt, Andrew R.
    BRITISH JOURNAL OF HAEMATOLOGY, 2013, 160 (01) : 53 - 62
  • [23] TP53 mutation and 17p deletion are associated with poor survival in patients with CLL irrespective of the inactivation of the other allele by deletion or TP53 mutation:: Results from a single center analysis
    Zenz, T.
    Haebe, S.
    Kroeber, A.
    Benner, A.
    Kienle, D.
    Buehler, A.
    Denzel, T.
    Winkler, D.
    Doehner, H.
    Stilgenbauer, S.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2007, 92 : 35 - 35
  • [24] TP53 GENE-MUTATIONS AND 17P DELETIONS IN HUMAN ASTROCYTOMAS
    CHUNG, R
    WHALEY, J
    KLEY, N
    ANDERSON, K
    LOUIS, DN
    MENON, A
    HETTLICH, C
    FREIMAN, R
    HEDLEYWHYTE, ET
    MARTUZA, R
    JENKINS, R
    YANDELL, D
    SEIZINGER, BR
    GENES CHROMOSOMES & CANCER, 1991, 3 (05): : 323 - 331
  • [25] Overall survival among patients diagnosed with B-chronic lymphocytic leukemia with 17p deletion status (del(17p))
    Katalinic, D.
    Toetome, L.
    Bildat, S.
    Kattner, E.
    Aleric, I.
    Vcev, A.
    ONCOLOGY RESEARCH AND TREATMENT, 2019, 42 : 223 - 223
  • [26] Prognostic Impact of TP53 Mutation in Combination with Chromosome 17p Deletion in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
    Yun, Seongseok
    Sandoval-Sus, Jose
    Knepper, Todd C.
    Teer, Jamie
    Chavez, Julio C.
    Pinilla-Ibarz, Javier
    BLOOD, 2017, 130
  • [27] Multiple Myeloma with a Deletion of Chromosome 17p: TP53 Mutations Are Highly Prevalent and Negatively Affect Prognosis
    Bruinink, Davine Hofste Op
    Remco, Hoogenboezem
    Sanders, Mathijs A.
    Wardell, Christopher P.
    Ashby, Cody
    Bindels, Eric M. J.
    Erpelinck-Verschueren, Claudia
    van Strien, Paulette
    Koenders, Jasper
    Kavelaars, Francois G.
    He, Jie
    Bailey, Mark
    Mughal, Tariq I.
    Misund, Kristine
    Beverloo, Berna
    van der Holt, Bronno
    Touw, Ivo
    Waage, Anders
    Avet-Loiseau, Herve
    Jackson, Graham H.
    Morgan, Gareth J.
    Walker, Brian A.
    Sonneveld, Pieter
    BLOOD, 2016, 128 (22)
  • [28] Pediatric brain tumors:: Loss of heterozygosity at 17p and TP53 gene mutations
    Orellana, C
    Hernandez-Martí, M
    Martínez, F
    Castel, V
    Millán, JM
    Alvarez-Garijo, JA
    Prieto, F
    Badía, L
    CANCER GENETICS AND CYTOGENETICS, 1998, 102 (02) : 93 - 99
  • [29] TP53 Protein Expression, But Not 17p13 Deletion, is Useful in Rapid Screening and Triage of TP53 Mutation in Acute Myeloid Leukemia
    Nwaoduah, Nneamaka
    Bernabeu, Belen Quereda
    Wang, Zixuan
    Liu, Jinglan
    Uppal, Guldeep
    Peiper, Stephen
    Gong, Jerald
    MODERN PATHOLOGY, 2018, 31 : 541 - 541
  • [30] TP53 Protein Expression, But Not 17p13 Deletion, is Useful in Rapid Screening and Triage of TP53 Mutation in Acute Myeloid Leukemia
    Nwaoduah, Nneamaka
    Bernabeu, Belen Quereda
    Wang, Zixuan
    Liu, Jinglan
    Uppal, Guldeep
    Peiper, Stephen
    Gong, Jerald
    LABORATORY INVESTIGATION, 2018, 98 : 541 - 541