Evaluation of clinical aspects and quality of life as risk factors for depression in patients with epilepsy

被引：21

作者：

Zhao, Ting ^{[1
]}

Sun, Ming-yue ^{[1
]}

Yu, Pei-min ^{[1
]}

Zhu, Guo-xing ^{[1
]}

Tang, Xing-hua ^{[1
]}

Shi, Yun-bo ^{[1
]}

Hong, Zhen ^{[1
]}

机构：

[1] Fudan Univ, Inst Neurol, Huashan Hosp, Shanghai 200040, Peoples R China

来源：

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2012年 / 21卷 / 05期

关键词：

Epilepsy; Depression; Risk factors; Quality of life; 5-HT1A RECEPTOR-BINDING; COMORBID DEPRESSION; PEOPLE; PREVALENCE; DISORDERS; ANXIETY; IMPACT;

D O I：

10.1016/j.seizure.2012.03.006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The purpose of this study was to investigate clinical aspects and quality of life (QOL) as risk factors for depression in patients with epilepsy. One hundred and forty outpatients with a diagnosis of epilepsy who were attending our epilepsy center participated. Patients anonymously filled out a questionnaire with clinical data related to epilepsy. Depression level was evaluated by the Hamilton Depression Rating Scale-17 (HAMD-17), and quality of life was evaluated by the Quality of Life in Epilepsy-31 (QOLIE-31). Thirty-six patients with epilepsy suffered from depression (25.7%). Complex partial seizures (OR = 0.112) and number of seizure types (OR = 3.773) were found to be clinical risk factors for depression. Low scores for seizure worry (OR = 0.947) and social function (OR = 0.947) on the QOLIE-31 increased the probability of depression in patients with epilepsy. (C) 2012 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

引用

页码：367 / 370

页数：4

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