GADD45A RECRUITS DEMETHYLATION PROTEINS TO CpG ISLAND PROMOTERS

被引：0
|
作者：
不详
机构：
来源：
CANCER DISCOVERY | 2019年 / 9卷 / 03期
关键词：
D O I：
10.1158/2159-8290.CD-RW2019-009
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
GADD45A binding to R-loops promotes TET1 recruitment and DNA demethylation at CpG island promoters. ©2019 American Association for Cancer Research.
引用
收藏
页码：315 / 315
页数：1
相关论文
共 50 条
  • [41] New role and molecular mechanism of Gadd45a in hepatic fibrosis
    Hong, Liang
    Sun, Qing-Feng
    Xu, Ting-Yan
    Wu, Yang-He
    Zhang, Hui
    Fu, Rong-Quan
    Cai, Fu-Jing
    Zhou, Qing-Qing
    Zhou, Ke
    Du, Qing-Wei
    Zhang, Dong
    Xu, Shuang
    Ding, Ji-Guang
    WORLD JOURNAL OF GASTROENTEROLOGY, 2016, 22 (09) : 2779 - 2788
  • [42] GADD45a physically and functionally interacts with TET1
    Kienhoefer, Sabine
    Musheev, Michael U.
    Stapf, Ulrike
    Helm, Mark
    Schomacher, Lars
    Niehrs, Christof
    Schaefer, Andrea
    DIFFERENTIATION, 2015, 90 (1-3) : 59 - 68
  • [43] A novel role of Gadd45a in base excision repair: enhancement of APE1 activity via protein-protein interactions of Gadd45a and PCNA
    Kim, Hve Lim
    Seo, Young Rok
    MOLECULAR & CELLULAR TOXICOLOGY, 2010, 6 (03) : 53 - 53
  • [44] Down-regulation of GADD45A enhances chemosensitivity in melanoma
    Liu, Jia
    Jiang, Guoqiang
    Mao, Ping
    Zhang, Jing
    Zhang, Lin
    Liu, Likun
    Wang, Jia
    Owusu, Lawrence
    Ren, Baoyin
    Tang, Yawei
    Li, Weiling
    SCIENTIFIC REPORTS, 2018, 8
  • [45] PML/RARα抑制GADD45A的转录表达
    饶玉清
    王侃侃
    张济
    上海交通大学学报(医学版), 2012, 32 (11) : 1466 - 1471
  • [46] The role of Gadd45a in the survival of human melanocytes and melanoma cells
    Voeltzel, Thibault
    Pourchet, Julie
    Mafille, Julien
    Fayolle, Caroline
    Puisieux, Alain
    de Fromentel, Claude Caron
    Dore, Jean-Francois
    PIGMENT CELL & MELANOMA RESEARCH, 2008, 21 (02) : 304 - 304
  • [47] Gadd45a is a Protective Modifier of Neurogenic Skeletal Muscle Atrophy
    Ehmsen, Jeffrey
    Kawaguchi, Riki
    Mi, Ruifa
    Kaval, Damlanur
    Ming, Guo-Li
    ANNALS OF NEUROLOGY, 2019, 86 : S198 - S198
  • [48] Gadd45a is a heterochromatin relaxer that enhances iPS cell generation
    Chen, Keshi
    Long, Qi
    Wang, Tao
    Zhao, Danyun
    Zhou, Yanshuang
    Qi, Juntao
    Wu, Yi
    Li, Shengbiao
    Chen, Chunlan
    Zeng, Xiaoming
    Yang, Jianguo
    Zhou, Zisong
    Qin, Weiwen
    Liu, Xiyin
    Li, Yuxing
    Li, Yingying
    Huang, Xiaofen
    Qin, Dajiang
    Chen, Jiekai
    Pan, Guangjin
    Schoeler, Hans R.
    Xu, Guoliang
    Liu, Xingguo
    Pei, Duanqing
    EMBO REPORTS, 2016, 17 (11) : 1641 - 1656
  • [49] Gadd45a Levels in Breast Cancer Are Hormone Receptor Dependent
    Willis, Alliric
    Powers, Benjamin
    Tront, Jennifer
    Smith, Geoffrey
    Hoffman, Barbara
    Liebermann, Daniel
    ANNALS OF SURGICAL ONCOLOGY, 2012, 19 : 118 - 118
  • [50] New role and molecular mechanism of Gadd45a in hepatic fibrosis
    Liang Hong
    Qing-Feng Sun
    Ting-Yan Xu
    Yang-He Wu
    Hui Zhang
    Rong-Quan Fu
    Fu-Jing Cai
    Qing-Qing Zhou
    Ke Zhou
    Qing-Wei Du
    Dong Zhang
    Shuang Xu
    Ji-Guang Ding
    World Journal of Gastroenterology, 2016, 22 (09) : 2779 - 2788
12345