Genetic deletion of the E3 ubiquitin ligase SIAH2 lowers hypoxia-induced apoptosis and reduces infarct size after coronary artery ligation

被引：0
|
作者：
Pironti, G. [1 ]
Perrino, C. [1 ]
Schiattarella, G. G. [1 ]
Gargiulo, G. [1 ]
Cannavo, A. [1 ]
Franzone, A. [1 ]
Sannino, A. [1 ]
Scudiero, L. [1 ]
Scognamiglio, A. [1 ]
Esposito, G. [1 ]
机构：
[1] Univ Hosp Federico II, Naples, Italy
来源：
EUROPEAN HEART JOURNAL | 2011年 / 32卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：692 / 692
页数：1
相关论文
共 32 条
  • [11] Downregulation of SIAH2, an ubiquitin E3 ligase, is associated with resistance to endocrine therapy in breast cancer
    Maurice P. H. M. Jansen
    Kirsten Ruigrok-Ritstier
    Lambert C. J. Dorssers
    Iris L. van Staveren
    Maxime P. Look
    Marion E. Meijer-van Gelder
    Anieta M. Sieuwerts
    Jozien Helleman
    Stefan Sleijfer
    Jan G. M. Klijn
    John A. Foekens
    Els M. J. J. Berns
    Breast Cancer Research and Treatment, 2009, 116 : 263 - 271
  • [12] Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2
    Nakayama, Koh
    Gazdoiu, Stefan
    Abraham, Robert
    Pan, Zhen-Qiang
    Ronai, Ze'ev
    BIOCHEMICAL JOURNAL, 2007, 401 : 217 - 226
  • [13] Downregulation of SIAH2, an ubiquitin E3 ligase, is associated with resistance to endocrine therapy in breast cancer
    Jansen, Maurice P. H. M.
    Ruigrok-Ritstier, Kirsten
    Dorssers, Lambert C. J.
    van Staveren, Iris L.
    Look, Maxime P.
    Meijer-van Gelder, Marion E.
    Sieuwerts, Anieta M.
    Helleman, Jozien
    Sleijfer, Stefan
    Klijn, Jan G. M.
    Foekens, John A.
    Berns, Els M. J. J.
    BREAST CANCER RESEARCH AND TREATMENT, 2009, 116 (02) : 263 - 271
  • [14] Downregulated expression of SIAH2, an ubiquitin E3 ligase, is associated with endocrine therapy failure.
    Jansen, M. P.
    Ritstier, K.
    Dorssers, L. C.
    van Staveren, I. L.
    Helleman, J.
    Look, M. P.
    Meijer-van Gelder, M. E.
    Sieuwerts, A. M.
    Portengen, H.
    Klijn, J. G.
    Foekens, J. A.
    Berns, E. M.
    BREAST CANCER RESEARCH AND TREATMENT, 2007, 106 : S120 - S120
  • [15] The E3 Ubiquitin Ligases Siah2 Contributes To Imatinib Resistance In Chronic Myeloid Leukemia In Hypoxia Condition
    Xu, Na
    Xiao, Xiaozhen
    Xiao, Yajuan
    Zhou, Xuan
    Gao, Guanlun
    Huang, Fen
    Xu, Dan
    Zhou, Hongsheng
    Xu, Bing
    Liu Xiaoli
    BLOOD, 2013, 122 (21)
  • [16] Regulation of death receptor-mediated apoptosis by the RING-Finger E3 ligase Siah2
    Christian, Perry
    Schwarze, Steven
    CANCER RESEARCH, 2009, 69
  • [17] Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH
    Perry A Christian
    Michael V Fiandalo
    Steven R Schwarze
    Molecular Cancer, 10
  • [18] Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH
    Christian, Perry A.
    Fiandalo, Michael V.
    Schwarze, Steven R.
    MOLECULAR CANCER, 2011, 10
  • [19] Targeting ADT-Induced Activation of the E3 Ubiquitin Ligase Siah2 to Delay the Occurrence of Castration-Resistant Prostate Cancer
    Yan, Tingmang
    Zhou, Dapeng
    Shi, Youwei
    Cui, Di
    Jiang, Juntao
    Han, Bangmin
    Xia, Shujie
    Wang, Zhou
    Liu, Haitao
    Guo, Wenhuan
    Jing, Yifeng
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [20] The E3 Ubiquitin Ligase Siah2 Contributes to Castration-Resistant Prostate Cancer by Regulation of Androgen Receptor Transcriptional Activity
    Qi, Jianfei
    Tripathi, Manisha
    Mishra, Rajeev
    Sahgal, Natasha
    Fazil, Ladan
    Ettinger, Susan
    Placzek, William J.
    Claps, Giuseppina
    Chung, Leland W. K.
    Bowtell, David
    Gleave, Martin
    Bhowmick, Neil
    Ronai, Ze'ev A.
    CANCER CELL, 2013, 23 (03) : 332 - 346
1234