Microwave-assisted synthesis of 5,6-dihydroindolo[1,2-a] quinoxaline derivatives through copper-catalyzed intramolecular N-arylation

被引：7

作者：

Zhao, Fei ^{[1
]}

Zhang, Lei ^{[1
]}

Liu, Hailong ^{[1
]}

Zhou, Shengbin ^{[1
]}

Liu, Hong ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 9卷

基金：

中国国家自然科学基金;

关键词：

copper; 5,6-dihydroindolo[1,2-a]quinoxaline; intramolecular N-arylation; microwave irradiation; INDOLE ALKALOIDS; HETEROCYCLES; CHEMISTRY; EFFICIENT; CASCADE; AMINES; MILD; CUI;

D O I：

10.3762/bjoc.9.285

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and practical protocol has been developed to synthesize 5,6-dihydroindolo[ 1,2-a] quinoxaline derivatives by CuI-catalyzed intramolecular N-arylation under microwave irradiation. This method rapidly afforded the tetracyclic products with good to excellent yields (83-97%) in short reaction times (45-60 min).

引用

页码：2463 / 2469

页数：7

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