Copper-Catalyzed Microwave-Assisted Synthesis of Benzimidazole Derivatives

被引：4

作者：

Ke, Fang ^{[1
]}

Xu, Jianhua ^{[1
]}

Liu, Caiqin ^{[1
]}

Li, Qian ^{[1
]}

Wu, Wen ^{[2
]}

Li, Peng ^{[1
]}

机构：

[1] Fujian Med Univ, Dept Pharm, Fuzhou 350004, Peoples R China

[2] Xiamen Matern & Child Care Hosp, Xiamen 361003, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 34卷 / 09期

基金：

中国国家自然科学基金;

关键词：

microwave-assisted synthesis; 2-haloaniline; amidine; benzimidazole; CASCADE REACTIONS; EFFICIENT; PROGRESS;

D O I：

10.6023/cjoc201404016

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, efficient, inexpensive and powerful microwave-assisted method for the Cu-catalyzed reactions of 2-haloanilines with amidines was developed by using cheap CuI as catalyst, inexpensive and readily available 8-hydroxyquinoline as ligand, and N,N-dimethylformamide (DMF) as solvent at 100 degrees C. Most target products were obtained in good to excellent yields.

引用

页码：1900 / 1904

页数：5

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