Quality of life in people with ongoing symptoms of coeliac disease despite adherence to a strict gluten-free diet

被引：17
|
作者：
Harnett, Joanna E. [1 ]
Myers, Stephen P. [2 ]
机构：
[1] Univ Sydney, Sch Pharm, Fac Med & Hlth, Sydney, NSW, Australia
[2] Southern Cross Univ, Div Res, NatMed Res, Lismore, NSW, Australia
来源：
SCIENTIFIC REPORTS | 2020年 / 10卷 / 01期
关键词：
GASTROINTESTINAL SYMPTOMS; ADULT PATIENTS; DEPRESSION;
D O I：
10.1038/s41598-020-58236-8
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
People with Coeliac disease who suffer persistent symptoms despite adherence to a gluten-free diet are at a greater risk of a reduced health related quality of life. The purpose of this paper is to report the quality of life experienced by this specific group of patients in Australia. A Coeliac Disease Specific Questionnaire (CDQ) was administered to 45 people who were enrolled in a clinical trial and reported persistent symptoms of Coeliac disease despite adherence to a strict gluten free diet. The clinical trial was based in New South Wales, Australia. The instrument used was a subscale and total scores of a CDQ measuring health related quality of life. At baseline the overall mean CDQ score was 147 +/- 3.31 (optimum 196) consisting of 4 subscales; gastrointestinal 33 +/- 0.88, emotional 32.9 +/- 0.99, worries 39.8 +/- 0.79 and social 41 +/- 6.12 each with a potential score of 49. The health related quality of life of people reporting persistent symptoms of Coeliac disease despite adherence to a gluten free diet is sub-optimal with concerningly low scores for emotional quality.
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页数：5
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