Quality of life in people with ongoing symptoms of coeliac disease despite adherence to a strict gluten-free diet

被引：17

作者：

Harnett, Joanna E. ^{[1
]}

Myers, Stephen P. ^{[2
]}

机构：

[1] Univ Sydney, Sch Pharm, Fac Med & Hlth, Sydney, NSW, Australia

[2] Southern Cross Univ, Div Res, NatMed Res, Lismore, NSW, Australia

来源：

SCIENTIFIC REPORTS | 2020年 / 10卷 / 01期

关键词：

GASTROINTESTINAL SYMPTOMS; ADULT PATIENTS; DEPRESSION;

D O I：

10.1038/s41598-020-58236-8

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

People with Coeliac disease who suffer persistent symptoms despite adherence to a gluten-free diet are at a greater risk of a reduced health related quality of life. The purpose of this paper is to report the quality of life experienced by this specific group of patients in Australia. A Coeliac Disease Specific Questionnaire (CDQ) was administered to 45 people who were enrolled in a clinical trial and reported persistent symptoms of Coeliac disease despite adherence to a strict gluten free diet. The clinical trial was based in New South Wales, Australia. The instrument used was a subscale and total scores of a CDQ measuring health related quality of life. At baseline the overall mean CDQ score was 147 +/- 3.31 (optimum 196) consisting of 4 subscales; gastrointestinal 33 +/- 0.88, emotional 32.9 +/- 0.99, worries 39.8 +/- 0.79 and social 41 +/- 6.12 each with a potential score of 49. The health related quality of life of people reporting persistent symptoms of Coeliac disease despite adherence to a gluten free diet is sub-optimal with concerningly low scores for emotional quality.

引用

页数：5

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