Synthesis and antioxidant activity of a novel class of fluorescein-based β-C-glycosides

被引：11
|
作者：
Rajasekar, Mani [1 ]
Das, Thangamuthu Mohan [1 ,2 ]
机构：
[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India
[2] CUTN, Sch Basic & Appl Sci, Dept Chem, Thiruvarur 610004, India
来源：
CARBOHYDRATE RESEARCH | 2013年 / 379卷
关键词：
Fluorescein derivatives; beta-C-glycosides; Aldol condensation; Antioxidant activity; CONDENSATION; ANALOG;
D O I：
10.1016/j.carres.2013.06.016
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A series of fluorescein-based beta-C-glycosyl ketones were synthesized through aldol condensation of beta-C-glycosyl ketones with fluorescein monoaldehyde under ambient reaction conditions in good yields. Formation of the expected product has been confirmed through different spectral techniques. Fluorescein-based beta-C-glycosides show moderate anti-oxidant activities with maximum inhibitory activity of 60%. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：38 / 42
页数：5
相关论文
共 50 条
  • [1] Studies on the synthesis and the antimicrobial and antioxidant activities of a novel class of fluorescein-based glycosides
    Rajasekar, Mani
    Jegadeesh, Raman
    Raaman, Nanjian
    Das, Thangamuthu Mohan
    CARBOHYDRATE RESEARCH, 2011, 346 (15) : 2362 - 2367
  • [2] Synthesis and Antioxidant Properties of Novel Fluorescein-Based Quinoline Glycoconjugates
    Rajasekar, Mani
    Das, Thangamuthu Mohan
    JOURNAL OF CARBOHYDRATE CHEMISTRY, 2014, 33 (03) : 137 - 151
  • [3] Synthesis and antihyperglycemic activity of phenolic C-glycosides
    Rawat, Preeti
    Kumar, Manmeet
    Rahuja, Neha
    Srivastava, Daya Shankar Lal
    Srivastava, Arvind Kumar
    Maurya, Rakesh
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (01) : 228 - 233
  • [4] Design, synthesis, and biological evaluation of a novel class of fluorescein-based N-glycosylamines
    Rajasekar, Mani
    Khan, Sulaiman Mahaboob
    Devaraj, Sivasithamparam Niranjali
    Das, Thangamuthu Mohan
    CARBOHYDRATE RESEARCH, 2011, 346 (13) : 1776 - 1785
  • [5] Flavonoid C-glycosides from star fruit and their antioxidant activity
    Yang, Dan
    Xie, Haihui
    Jia, Xuchao
    Wei, Xiaoyi
    JOURNAL OF FUNCTIONAL FOODS, 2015, 16 : 204 - 210
  • [6] SYNTHESIS OF NOVEL FUSED-RING C-GLYCOSIDES
    LEVY, DE
    DASGUPTA, F
    TANG, PC
    TETRAHEDRON-ASYMMETRY, 1994, 5 (11) : 2265 - 2268
  • [7] Synthesis of nojirimycin C-glycosides
    Cipolla, L
    Palma, A
    La Ferla, B
    Nicotra, F
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 2002, (19): : 2161 - 2165
  • [8] NEW SYNTHESIS OF C-GLYCOSIDES
    CZERNECKI, S
    GRUY, F
    TETRAHEDRON LETTERS, 1981, 22 (05) : 437 - 440
  • [9] SYNTHESIS OF NEW C-GLYCOSIDES
    ZHDANOV, IA
    DOROFEENKO, IN
    KOROLCHENKO, GA
    BOGDANOVA, GV
    DOKLADY AKADEMII NAUK SSSR, 1963, 152 (01): : 102 - &
  • [10] Synthesis, screening and sensing applications of a novel fluorescent probe based on C-glycosides
    Zhang, Tao
    Wang, Tianyi
    Fang, Zhijie
    RSC ADVANCES, 2016, 6 (22): : 18357 - 18363
12345