A 23-year-old male presented with renal failure, cholestatic liver enzyme elevation and uveitis. Percutaneous renal biopsy revealed marked eosinophilic infiltration of the renal interstitium, which made the diagnosis of TINU syndrome (Tubulo-Interstitial Nephritis and Uveitis). Percutaneous liver biopsy showed granulomatous hepatitis, which was not described as a part of TINU syndrome. The diagnostic dilemma and the literature are discussed.
机构:
Great Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, EnglandGreat Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, England
Stewart, Douglas J.
Sekar, Thivya
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Great Ormond St Hosp Children NHS Fdn Trust, Dept Histopathol, London WC1N 3JH, EnglandGreat Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, England
Sekar, Thivya
Tullus, Kjell
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Great Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, EnglandGreat Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, England
机构:
Great Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, EnglandGreat Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, England
Stewart, Douglas J.
Sekar, Thivya
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Great Ormond St Hosp Children NHS Fdn Trust, Dept Histopathol, London WC1N 3JH, EnglandGreat Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, England
Sekar, Thivya
Tullus, Kjell
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Great Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, EnglandGreat Ormond St Hosp Children NHS Fdn Trust, Dept Paediat Nephrol, London WC1N 3JH, England
机构:
Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101
Weinstein O.
Tovbin D.
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机构:
Department of Nephrology, Soroka University Medical Center, Beer Sheva 84101Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101
Tovbin D.
Rogachev B.
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机构:
Department of Nephrology, Soroka University Medical Center, Beer Sheva 84101Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101
Rogachev B.
Basok A.
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机构:
Department of Nephrology, Soroka University Medical Center, Beer Sheva 84101Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101
Basok A.
Vorobiov M.
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机构:
Department of Nephrology, Soroka University Medical Center, Beer Sheva 84101Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101
Vorobiov M.
Kratz A.
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Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101
Kratz A.
Lifshitz T.
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Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101
Lifshitz T.
Zlotnik M.
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Department of Nephrology, Soroka University Medical Center, Beer Sheva 84101Department of Ophthalmology, Soroka University Medical Center, Beer Sheva 84101
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Antrim Area Hosp, Nephrol Unit, 45 Bush Rd, Antrim BT41 2RL, Antrim, North IrelandAntrim Area Hosp, Nephrol Unit, 45 Bush Rd, Antrim BT41 2RL, Antrim, North Ireland
Sinnamon, Kim T.
Courtney, Aisling E.
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机构:
Belfast City Hosp, Reg Nephrol Unit, Belfast BT9 7AB, Antrim, North IrelandAntrim Area Hosp, Nephrol Unit, 45 Bush Rd, Antrim BT41 2RL, Antrim, North Ireland
Courtney, Aisling E.
Harron, Camille
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Antrim Area Hosp, Nephrol Unit, 45 Bush Rd, Antrim BT41 2RL, Antrim, North IrelandAntrim Area Hosp, Nephrol Unit, 45 Bush Rd, Antrim BT41 2RL, Antrim, North Ireland
Harron, Camille
O'Rourke, Declan M.
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Belfast City Hosp, Dept Pathol, Belfast BT9 7AB, Antrim, North IrelandAntrim Area Hosp, Nephrol Unit, 45 Bush Rd, Antrim BT41 2RL, Antrim, North Ireland
O'Rourke, Declan M.
Mullan, Robert N.
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Antrim Area Hosp, Nephrol Unit, 45 Bush Rd, Antrim BT41 2RL, Antrim, North IrelandAntrim Area Hosp, Nephrol Unit, 45 Bush Rd, Antrim BT41 2RL, Antrim, North Ireland