Recent progress in the Morita-Baylis-Hillman reactions

被引：61

作者：

Iwabuchi, Y ^{[1
]}

Hatakeyama, S ^{[1
]}

机构：

[1] Nagasaki Univ, Fac Pharmaceut Sci, Nagasaki 8526521, Japan

来源：

JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN | 2002年 / 60卷 / 01期

关键词：

Morita-Baylis-Hillman reaction; nucleophilic catalysis; rate enhancement; asymmetric synthesis; asymmetric catalysis; diastereoselective reaction; amine catalyst; phosphine catalyst; calcogeno-Baylis-Hillman reactions; tandem Michael-aldol reaction; enzymatic resolution; kinetic resolution;

D O I：

10.5059/yukigoseikyokaishi.60.2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Morita-Baylis-Hillman reaction, alpha-hydroxyalkylation of activated olefins, has attracted considerable research interest because of the synthetic utility of the densely functionalized product as well as the exquisite tandem Michael-aldol reaction process under nucleophilic catalysis. This review gives an overview on recent remarkable progress in the Morita-Baylis-Hillman reactions. Several other successful methods affording the Morita-Baylis-Hillman type adducts are also reviewed by focusing their imaginative strategies.

引用

页码：2 / 14

页数：13

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