Methionine restriction forces Epstein-Barr virus out of latency

被引：1
|
作者：
Kashyap, Sriraksha Bharadwaj [1 ]
Mulondo, Racheal [1 ]
Mullen, Peter J. [1 ,2 ,3 ]
机构：
[1] Univ Southern Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90089 USA
[2] Univ Southern Calif, Leonard Davis Sch Gerontol, Los Angeles, CA 90089 USA
[3] Univ Southern Calif, Norris Comprehens Canc Ctr, Keck Sch Med, Los Angeles, CA 90089 USA
来源：
CELL METABOLISM | 2022年 / 34卷 / 09期
关键词：
D O I：
10.1016/j.cmet.2022.08.009
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
EBV gene expression is repressed during viral latency to prevent an immune response, but it is not known how metabolism contributes to this silencing. In this issue of Cell Metabolism, Guo et al. describe how methionine restriction reactivates the expression of EBV genes, offering new therapeutic approaches against EBV-driven diseases.
引用
收藏
页码：1229 / +
页数：3
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