The effects of malaria control on nutritional status in infancy

被引:31
|
作者
Snow, RW
Molyneux, CS
Njeru, EK
Omumbo, J
Nevill, CG
Muniu, E
Marsh, K
机构
[1] KENYA GOVT MED RES CTR, CLIN RES CTR, KILIFI UNIT, KILIFI, KENYA
[2] UNIV OXFORD, JOHN RADCLIFFE HOSP, NUFFIELD DEPT CLIN MED, OXFORD OX3 9DU, ENGLAND
[3] UNIV NAIROBI, FAC MED, NAIROBI CLIN EPIDEMIOL UNIT, DEPT COMMUNITY HLTH, NAIROBI, KENYA
[4] AFRICAN MED & RES FDN, NAIROBI, KENYA
[5] KENYA GOVT MED RES CTR, MED RES CTR, NAIROBI, KENYA
基金
英国惠康基金;
关键词
childhood; insecticide-treated bed nets; malaria; nutrition;
D O I
10.1016/S0001-706X(96)00601-8
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Both malaria and undernutrition are major causes of paediatric mortality and morbidity in sub-Saharan Africa. The introduction of insecticide-treated bed nets (ITBN) during a randomized controlled trial on the Kenyan coast significantly reduced severe, life-threatening malaria and all-cause childhood mortality. This paper describes the effects of the intervention upon the nutritional status of infants aged between 1 and 11 months of age. Seven hundred and eighty seven infants who slept under ITBN and 692 contemporaneous control infants, were seen during one of three cross-sectional surveys conducted during a one year period. Standardized weight-for-age and mid-upper arm circumference measures were significantly higher among infants who used ITBN compared with control infants. Whether these improvements in markers of nutritional status were a direct result of concomitant reductions in clinical malaria episodes remains uncertain. Never-the-less evidence suggests that even moderate increases in weight-for-age scores can significantly reduce the probability of mortality in childhood and ITBN may provide additional gains to child survival,beyond their impressive effects upon malaria-specific events. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:1 / 10
页数:10
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