Synthetic Glycans, Glycoarrays, and Glyconanoparticles To Investigate Host Infection by Trypanosoma cruzi

被引：0

作者：

Field, Robert A. ^{[1
,2
]}

Andrade, Peterson ^{[3
]}

Campo, Vanessa L. ^{[3
]}

Carvalho, Ivone ^{[3
]}

Collet, Beatrice Y. M. ^{[2
]}

Crocker, Paul R. ^{[4
]}

Fais, Margherita ^{[1
,2
]}

Karamanska, Rositsa ^{[1
,2
]}

Mukhopadhayay, Balaram ^{[2
]}

Nepogodiev, Sergey A. ^{[1
,2
]}

Rashid, Abdul ^{[1
]}

Rejzek, Martin ^{[1
]}

Russell, David A. ^{[2
]}

Schofield, Claire L. ^{[2
]}

van Well, Renate M. ^{[2
]}

机构：

[1] John Innes Inst, Dept Biol Chem, Norwich Res Pk, Norwich NR4 7UH, Norfolk, England

[2] Univ East Anglia, Sch Chem, Norwich NR4 7TJ, England

[3] Faculdade Ciencias Farmaceut Ribeirao Preto, USP, BR-14040903 Ribeirao Preto, SP, Brazil

[4] Univ Dundee, Div Cell Biol & Immunol, Coll Life Sci, Wellcome Trust Bioctr, Dundee DD1 5EH, Scotland

来源：

PETITE AND SWEET: GLYCO-NANOTECHNOLOGY AS A BRIDGE TO NEW MEDICINES | 2011年 / 1091卷

基金：

英国工程与自然科学研究理事会;

关键词：

SURFACE TRANS-SIALIDASE; COLORIMETRIC DETECTION; CHEMOENZYMATIC SYNTHESIS; GOLD GLYCONANOPARTICLES; MUCINS; DRUG; OLIGOSACCHARIDES; NANOMATERIALS; GLYCOPROTEIN; MECHANISM;

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Carbohydrate libraries, synthetic glycans and glycopeptides are contributing to understanding of the role of sialic acid recognition in host infection by the parasite Trypanosoma cruzi. Further, glycoarray approaches are allowing us to explore similarities and differences in the carbohydrate-binding specificity of host lectins while glyconanoparticles enable us to ask questions about the structure, sialylation and recognition of parasite mucins.

引用

页码：143 / +

页数：5

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