Cytotoxic polyacetylenic alcohols from the marine sponge Petrosia species

被引：30

作者：

Lim, YJ

Lee, CO

Hong, JK

Kim, D

Im, KS

Jung, JH ^{[1
]}

机构：

[1] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea

[2] Korea Res Inst Chem Technol, Taejon 305606, South Korea

[3] Korea Basic Sci Inst, Taejon, South Korea

[4] Inje Univ, Dept Chem, Kimhae, South Korea

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 12期

关键词：

D O I：

10.1021/np010247p

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Now polyacetylenic alcohols (1-5) have been isolated as cytotoxic principles from the marine sponge Petrosia sp. The compounds were particularly cytotoxic against a human melanoma cell line (SK-MEL-2). The gross structures were established on the basis of NMR and MS data, and the absolute configuration was determined by the modified Mosher's method.

引用

页码：1565 / 1567

页数：3

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