Cytotoxic polyacetylenic alcohols from the marine sponge Petrosia species

被引：30
|
作者：
Lim, YJ
Lee, CO
Hong, JK
Kim, D
Im, KS
Jung, JH [1 ]
机构：
[1] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea
[2] Korea Res Inst Chem Technol, Taejon 305606, South Korea
[3] Korea Basic Sci Inst, Taejon, South Korea
[4] Inje Univ, Dept Chem, Kimhae, South Korea
来源：
JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 12期
关键词：
D O I：
10.1021/np010247p
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Now polyacetylenic alcohols (1-5) have been isolated as cytotoxic principles from the marine sponge Petrosia sp. The compounds were particularly cytotoxic against a human melanoma cell line (SK-MEL-2). The gross structures were established on the basis of NMR and MS data, and the absolute configuration was determined by the modified Mosher's method.
引用
收藏
页码：1565 / 1567
页数：3
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