Synthesis of novel pyrazolo[3,4-b]pyridines has been achieved successfully by sequence of Gould - Jacobs reaction between 5-aminopyrazole and diethylethoxymethylenemalonate in good yield. Further the pyrazolo[3,4-b]pyridines were converted into succinimidoyl active esters which are then replaced by biological samples such as amino acids and carbohydrate in slightly aqueous medium.
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Nankai Univ, Res Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R ChinaNankai Univ, Res Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
Zhao, WG
Li, ZM
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Nankai Univ, Res Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R ChinaNankai Univ, Res Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
Li, ZM
Yuan, DK
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Nankai Univ, Res Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R ChinaNankai Univ, Res Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China