Filter, collimator and moderating material to achieve boron neutron capture enhanced fast neutron therapy

被引：5
|
作者：
Sweezy, J
Hertel, N
Lennox, A
机构：
[1] Los Alamos Natl Lab, Div Appl Phys, Los Alamos, NM 87545 USA
[2] Georgia Inst Technol, Neely Nucl Res Ctr, Atlanta, GA 30332 USA
[3] Fermilab Neutron Therapy Facil, Batavia, IL 60510 USA
来源：
RADIATION PROTECTION DOSIMETRY | 2005年 / 116卷 / 1-4期
关键词：
D O I：
10.1093/rpd/nci256
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
The combination of fast neutron therapy and boron neutron capture therapy is currently being studied as a possible treatment for some radio-resistant brain tumours. In an attempt to design a boron-enhanced fast neutron therapy beam for the Fermilab Fast Neutron Therapy Facility, the use of moderating material surrounding the patient's head has been investigated. Graphite, polyethylene, water and heavy water were studied as moderating materials, using MCNP. The use of tungsten, iron, lead and bismuth as materials for a small filter and collimator near the patient's head was investigated. Calculations showed that a filter and collimator made of tungsten with a graphite moderator was capable of producing a dose enhancement of 17.3 +/- 0.6% for a 100 mu g g(-1) loading of B-10 for a 5.6 cm diameter beam while delivering 1.5 Gy in 7 min.
引用
收藏
页码：470 / 474
页数：5
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