Genomic structure of carp mitogen-activated protein kinase kinase 1 gene

被引：3
|
作者：
Leu, JH
Lee, MS
Chen, KT
Chang, GD
Chou, CK
Huang, CJ
机构：
[1] ACAD SINICA,INST BIOL CHEM,TAIPEI,TAIWAN
[2] GRAD INST BIOCHEM SCI,TAIPEI,TAIWAN
[3] NATL TAIWAN UNIV,TAIPEI 10764,TAIWAN
[4] NATL TAIWAN UNIV,DEPT SURG,UNIV HOSP,TAIPEI 10764,TAIWAN
[5] VET GEN HOSP,DEPT MED RES,TAIPEI 11217,TAIWAN
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1996年 / 1306卷 / 2-3期
关键词：
genomic DNA sequence; mitogen-activated protein kinase kinase; (Cyprinus carpio);
D O I：
10.1016/0167-4781(96)00023-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Carp mitogen-activated protein kinase kinase 1 (cMKK1) gene was isolated from a liver genomic library. The sequence around the exon-intron boundaries and 2 kb of the promoter region were determined. Our data indicate that this gene is composed of 11 exons and 10 introns spanning about 9 kb. Multiple potential transcription initiation sites were located by primer extension analysis. Examination of 2 kb of 5'-flanking sequence revealed potential binding sites for a variety of transcription factors such as E2F, Ets-1, GATA-1, Myb, NF-IL6, Sp1, and NF-kB.
引用
收藏
页码：133 / 136
页数：4
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