Epigenetic Variations in Heredity and Evolution

被引：39
|
作者：
Jablonka, E. [1 ]
机构：
[1] Tel Aviv Univ, Cohn Inst Hist & Philosophy Sci & Ideas, IL-69978 Tel Aviv, Israel
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 2012年 / 92卷 / 06期
关键词：
CAENORHABDITIS-ELEGANS; GENE-EXPRESSION; INHERITANCE; METHYLATION; ADAPTATION; PHENOTYPES; BEHAVIOR; WILD; RNAS;
D O I：
10.1038/clpt.2012.158
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The biological and medical importance of epigenetics is now taken for granted, but the significance of one aspect of it-epigenetic inheritance-is less widely recognized. New data suggest that not only is it ubiquitous, but both the generation and the transmission of epigenetic variations may be affected by developmental conditions. Population studies, formal models, and research on genomic and ecological stresses all suggest that epigenetic inheritance is important in both micro- and macroevolutionary change.
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页码：683 / 688
页数：6
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