Aim of the study: We aimed to compare the efficacy of the continuous use of thoracic epidural and intercostal analgesia for post-thoracotomy pain. Material and methods: Sixty patients completed a prospective, randomized, double-blinded study. The patients were randomized to receive thoracic epidural (group 1, n = 30) or intercostal block (group 2, n = 30) for 24 hours. In both groups, 0.25% bupivacaine was infused at a rate of 5 ml/h through an inserted catheter. Visual analog scale at rest (VAS-R) and after coughing (VAS-C) scores were recorded at baseline and at 1, 6 and 24 hours after surgery to evaluate pain. Morphine consumption, complications and side effects were recorded as well. Results: VAS-R and VAS-C scores were similar at baseline; however, 1st, 6th and 24th hour scores of group 1 were significantly lower than the scores of group 2 (for VAS-R; p = 0.017, p = 0.001, p = 0.023, for VAS-C; p = 0.006, p = 0.002, p = 0.032, respectively). 24-hour morphine consumption was lower in group 1 in comparison to group 2 (p = 0.032). In group 1, 5 out of 30 patients (17%) experienced hypotension, compared with none in group 2 (p = 0.02). Conclusions: For post-thoracotomy pain, better control of analgesia is observed with the thoracic epidural technique; however, intercostal block constitutes an alternative method as it is characterized by lower incidence of hypotension.
机构:
Dr D Y Patil Vidyapeeth, Dr D Y Patil Med Coll Hosp & Res Ctr, Anesthesiol, Pune, IndiaDr D Y Patil Vidyapeeth, Dr D Y Patil Med Coll Hosp & Res Ctr, Anesthesiol, Pune, India
Sharma, Vipul
Atluri, Harika
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Dr D Y Patil Vidyapeeth, Dr D Y Patil Med Coll Hosp & Res Ctr, Anesthesiol, Pune, IndiaDr D Y Patil Vidyapeeth, Dr D Y Patil Med Coll Hosp & Res Ctr, Anesthesiol, Pune, India
机构:
Barts Heart Ctr, Dept Perioperat Med, London, England
St Bartholomews Hosp, London, EnglandBarts Heart Ctr, Dept Perioperat Med, London, England
Wong, Jonathon
Cooper, Jackie
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Queen Mary Univ London, NIHR Biomed Res Ctr Barts, William Harvey Res Inst, London, EnglandBarts Heart Ctr, Dept Perioperat Med, London, England
Cooper, Jackie
Thomas, Rik
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Univ Coll London Hosp, Dept Perioperat Med, London, EnglandBarts Heart Ctr, Dept Perioperat Med, London, England
Thomas, Rik
Langford, Richard
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Barts Heart Ctr, Dept Perioperat Med, London, England
St Bartholomews Hosp, London, EnglandBarts Heart Ctr, Dept Perioperat Med, London, England
Langford, Richard
Anwar, Sibtain
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Barts Heart Ctr, Dept Perioperat Med, London, England
St Bartholomews Hosp, London, England
Queen Mary Univ London, NIHR Biomed Res Ctr Barts, William Harvey Res Inst, London, EnglandBarts Heart Ctr, Dept Perioperat Med, London, England