Splenomegaly and Variceal Bleeding in a Ten-year-old HIV-infected Girl With Noncirrhotic Portal Hypertension

被引：5

作者：

Giacomet, Vania ^{[1
]}

Vigano, Alessandra ^{[1
]}

Penagini, Francesca ^{[1
]}

Manfredini, Valeria ^{[1
]}

Maconi, Giovanni ^{[2
]}

Camozzi, Mario ^{[3
]}

Zuccotti, Gian Vincenzo ^{[1
]}

机构：

[1] Univ Milan, Dept Pediat, L Sacco Hosp, Milan, Italy

[2] Univ Milan, Dept Gastroenterol, L Sacco Hosp, Milan, Italy

[3] Osped Niguarda Ca Granda, Dept Pathol, Milan, Italy

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2012年 / 31卷 / 10期

关键词：

noncirrhotic portal hypertension; non-AIDS related comorbidities; pediatric HIV infection; NODULAR REGENERATIVE HYPERPLASIA; ANTIRETROVIRAL DRUGS; LIVER-DISEASE;

D O I：

10.1097/INF.0b013e3182694126

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Noncirrhotic portal hypertension is an uncommon liver disease of unknown origin, increasingly described in HIV-infected adults. Prolonged antiretroviral exposure, in particular to didanosine, and thrombophilic predisposition have been suggested as potential pathogenic factors. Data are limited in children. We describe a 10-year-old HIV-infected girl with noncirrhotic portal hypertension who presented with progressive spleen enlargement and variceal bleeding.

引用

页码：1059 / 1060

页数：2

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