Splenomegaly and Variceal Bleeding in a Ten-year-old HIV-infected Girl With Noncirrhotic Portal Hypertension

被引：5
|
作者：
Giacomet, Vania [1 ]
Vigano, Alessandra [1 ]
Penagini, Francesca [1 ]
Manfredini, Valeria [1 ]
Maconi, Giovanni [2 ]
Camozzi, Mario [3 ]
Zuccotti, Gian Vincenzo [1 ]
机构：
[1] Univ Milan, Dept Pediat, L Sacco Hosp, Milan, Italy
[2] Univ Milan, Dept Gastroenterol, L Sacco Hosp, Milan, Italy
[3] Osped Niguarda Ca Granda, Dept Pathol, Milan, Italy
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2012年 / 31卷 / 10期
关键词：
noncirrhotic portal hypertension; non-AIDS related comorbidities; pediatric HIV infection; NODULAR REGENERATIVE HYPERPLASIA; ANTIRETROVIRAL DRUGS; LIVER-DISEASE;
D O I：
10.1097/INF.0b013e3182694126
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Noncirrhotic portal hypertension is an uncommon liver disease of unknown origin, increasingly described in HIV-infected adults. Prolonged antiretroviral exposure, in particular to didanosine, and thrombophilic predisposition have been suggested as potential pathogenic factors. Data are limited in children. We describe a 10-year-old HIV-infected girl with noncirrhotic portal hypertension who presented with progressive spleen enlargement and variceal bleeding.
引用
收藏
页码：1059 / 1060
页数：2
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