Four differently substituted 2-aryl-2,3,4,5-tetrahydro-1H-1,4-epoxy-1-benzazepines: hydrogen-bonded structures in one, two and three dimensions

被引：10
|
作者：
Gomez, Sandra L. [2 ]
Sanabria, Carlos M. [2 ]
Palma, Alirio [2 ]
Bahsas, Ali [3 ]
Cobo, Justo [4 ]
Glidewell, Christopher [1 ]
机构：
[1] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland
[2] Univ Ind Santander, Escuela Quim, Lab Sintesis Organ, Bucaramanga 678, Colombia
[3] Univ Los Andes, Dept Quim, Grp Prod Nat, Lab RMN, Merida 5101, Venezuela
[4] Univ Jaen, Dept Quim Inorgan & Organ, Jaen 23071, Spain
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY | 2009年 / 65卷
关键词：
TETRAHYDRO-1,4-EPOXY-1-BENZAZEPINES;
D O I：
10.1107/S0108270109030339
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In (2RS, 4SR)-7-chloro-2-exo-(2-chloro-6-fluorophenyl)-2,3,4,5-tetrahydro-1H-1,4-epoxy-1-benzazepine, C16H12Cl2FNO, (I), molecules are linked into chains by a single C-H center dot center dot center dot pi(arene) hydrogen bond. (2RS, 4SR)-2-exo-(2-Chloro-6-fluorophenyl)2,3,4,5- tetrahydro-1H-1,4-epoxy-1-benzazepine, C16H13ClFNO, (II), is isomorphous with compound (I) but not strictly isostructural with it, as the hydrogen-bonded chains in (II) are linked into sheets by an aromatic pi-pi stacking interaction. The molecules of (2RS, 4SR)-7-methyl-2-exo-(4-methylphenyl)-2,3,4,5- tetrahydro-1H-1,4-epoxy-1-benzazepine, C18H19NO, (III), are linked into sheets by a combination of C-H center dot center dot center dot N and C-H center dot center dot center dot(arene) hydrogen bonds. (2S, 4R)-2-exo-(2-Chlorophenyl)- 2,3,4,5-tetrahydro-1H-1,4-epoxy-1-benzazepine, C16H14ClNO, (IV), crystallizes as a single enantiomer and the molecules are linked into a three-dimensional framework structure by a combination of one C-H center dot center dot center dot O hydrogen bond and three C-H center dot center dot center dot pi(arene) hydrogen bonds.
引用
收藏
页码：O465 / O469
页数：5
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